1-(4-Fluorobenzyl)-5-oxo-N-(3-(trifluoromethyl)phenyl)pyrrolidine-2-carboxamide CAS 59749-51-8
| CAS No. | 59749-51-8 |
| Molecular Formula | C19H16F4N2O2 |
| Molecular Weight | 380.34 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 1-(4-Fluorobenzyl)-5-oxo-N-(3-(trifluoromethyl)phenyl)pyrrolidine-2-carboxamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
1-(4-Fluorobenzyl)-5-oxo-N-(3-(trifluoromethyl)phenyl)pyrrolidine-2-carboxamide (CAS 59749-51-8) is a high-purity analytical reference standard with the molecular formula C19H16F4N2O2 and a molecular weight of 380.34 g/mol.
The molecular framework of 1-(4-Fluorobenzyl)-5-oxo-N-(3-(trifluoromethyl)phenyl)pyrrolidine-2-carboxamide (C19H16F4N2O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C19H16F4N2O2 |
| Molecular Weight | 380.34 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Fluorobenzyl Standards
- 2-((3-Fluorobenzyl)thio)-3-phenyl-6-(trifluoromethyl)pyrimidin-4(3H)-one (CAS 692287-48-2)
- 1-(4-Fluorobenzyl)-5-oxo-N-(4-oxo-4H-chromen-2-yl)pyrrolidine-2-carboxamide (CAS 59749-50-7)
- 2-((2-Fluorobenzyl)thio)-6-methyl-4-(trifluoromethyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile (CAS 626228-62-4)
- 3-(2-Fluorobenzyl)-6-iodoquinazolin-4(3H)-one (CAS 302913-41-3)
- (2-(2-((4-Fluorobenzyl)oxy)-5-(trifluoromethyl)phenyl)cyclopent-1-en-1-yl)boronic acid (CAS 612833-84-8)
- 4-[(4-Fluorobenzyl)oxy]benzyl 3-nitrobenzenecarboxylate (CAS 331461-75-7)
- 4-(4-Fluorobenzyl)-3-((4-methylbenzyl)thio)-5-(trifluoromethyl)-4H-1,2,4-triazole (CAS 866152-92-3)
- 5-((4-Fluorobenzyl)oxy)-4-oxo-N-(3-phenylpropyl)-4H-pyran-2-carboxamide (CAS 1021060-60-5)
Recommended Standards
- 1-(3-Amino-6-(benzo[d][1,3]dioxol-5-yl)-4-(trifluoromethyl)thieno[2,3-b]pyridin-2-yl)ethan-1-one (CAS 626221-00-9)
- 1-Amino-4-((4-(difluoromethoxy)phenyl)amino)anthracene-9,10-dione (CAS 62149-28-4)
- (2Z)-2-[4-(3-Fluoropropoxy)phenyl]-3-{[4-(trifluoromethoxy)phenyl]amino}prop-2-enenitrile (CAS 477888-58-7)
- 2-((5-(Pyridin-4-yl)-1,3,4-oxadiazol-2-yl)thio)-N-(2-(trifluoromethyl)phenyl)acetamide (CAS 884992-48-7)
- 3-Phenyl-4-(1H-tetrazol-1-yl)butanoic acid (CAS 632291-65-7)
- 7-Methoxy-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepine (CAS 215453-97-7)
- (1S,2R,4S,5R)-1-(2-(Benzhydrylamino)-2-oxoethyl)-2-((S)-hydroxy(quinolin-4-yl)methyl)-5-vinylquinuclidin-1-ium bromide (CAS 2937391-99-4)
- 1-(4-Aminophenyl)-2-(ethylsulfonyl)butan-1-one (CAS 1707376-20-2)
- 4-Cyclopropoxy-3-methoxybenzamide (CAS 1243406-49-6)
- Heptachlor epoxide Impurity 3 (CAS 145213-12-3)
- 4-(aminomethyl)-2,3-dihydro-1,3-thiazol-2-one hydrochloride (CAS 1394041-73-6)
- 85826-33-1 4,6-Dichloro-2-methyl-5-(prop-2-en-1-yl)pyrimidine DTXSID50517310 (CAS 85826-33-1)
- 5,7-Dimethoxybenzo[d]isothiazol-3(2H)-one 1,1-dioxide (CAS 64404-51-9)
- Exenatide (CAS 141758-74-9（free base）)
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