(2E)-3-{4-[(2,4-dichlorophenyl)methoxy]phenyl}-N-(3-methoxyphenyl)prop-2-enamide CAS 477888-76-9
| CAS No. | 477888-76-9 |
| Molecular Formula | C23H19Cl2NO3 |
| Molecular Weight | 428.31 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), (2E)-3-{4-[(2,4-dichlorophenyl)methoxy]phenyl}-N-(3-methoxyphenyl)prop-2-enamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
(2E)-3-{4-[(2,4-dichlorophenyl)methoxy]phenyl}-N-(3-methoxyphenyl)prop-2-enamide (CAS 477888-76-9), molecular formula C23H19Cl2NO3 and molecular weight 428.31 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (2E)-3-{4-[(2,4-dichlorophenyl)methoxy]phenyl}-N-(3-methoxyphenyl)prop-2-enamide (C23H19Cl2NO3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C23H19Cl2NO3 |
| Molecular Weight | 428.31 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related E Standards
- (2E)-3-{4-[(2,4-dichlorophenyl)methoxy]phenyl}-N-(4-methoxyphenyl)prop-2-enamide (CAS 477888-77-0)
- (2,4-Dichlorophenyl)(1-methyl-5-(5-(phenoxymethyl)-1,3,4-oxadiazol-2-yl)-1H-pyrrol-3-yl)methanone (CAS 338418-65-8)
- N-((2,4-dichlorophenyl)sulfonyl)-N-(3-(trifluoromethyl)phenyl)glycine (CAS 337922-15-3)
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- N-(5-(1-(2,6-Dichlorophenyl)-3-(difluoromethyl)-1H-pyrazol-5-yl)thiazol-2-yl)cyclopropanecarboxamide (CAS 1338247-30-5)
- (3Z)-3-{[(2,4-dichlorophenyl)methoxy]imino}-N-(4-phenoxyphenyl)propanamide (CAS 477851-47-1)
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