(2E)-3-{4-[(2,4-dichlorophenyl)methoxy]phenyl}-N-(2-methylphenyl)prop-2-enamide CAS 477888-75-8

Purity 97%+In StockPharmaceutical Standards
CAS No.477888-75-8
Molecular FormulaC23H19Cl2NO2
Molecular Weight412.31 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(2E)-3-{4-[(2,4-dichlorophenyl)methoxy]phenyl}-N-(2-methylphenyl)prop-2-enamide CAS 477888-75-8 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

(2E)-3-{4-[(2,4-dichlorophenyl)methoxy]phenyl}-N-(2-methylphenyl)prop-2-enamide (CAS 477888-75-8) is a high-purity analytical reference standard with the molecular formula C23H19Cl2NO2 and a molecular weight of 412.31 g/mol.

The molecular framework of (2E)-3-{4-[(2,4-dichlorophenyl)methoxy]phenyl}-N-(2-methylphenyl)prop-2-enamide (C23H19Cl2NO2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

CATO manufactures (2E)-3-{4-[(2,4-dichlorophenyl)methoxy]phenyl}-N-(2-methylphenyl)prop-2-enamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC23H19Cl2NO2
Molecular Weight412.31 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at room temperature, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)14.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentCl-containing
Nitrogen Atoms1

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