(E)-2-(1,1-dioxidothiomorpholino)-N'-(thiophen-2-ylmethylene)acetohydrazide CAS 477890-01-0
| CAS No. | 477890-01-0 |
| Molecular Formula | C11H15N3O3S2 |
| Molecular Weight | 301.39 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (E)-2-(1,1-dioxidothiomorpholino)-N'-(thiophen-2-ylmethylene)acetohydrazide.
(E)-2-(1,1-dioxidothiomorpholino)-N'-(thiophen-2-ylmethylene)acetohydrazide (CAS 477890-01-0) is a high-purity analytical reference standard with the molecular formula C11H15N3O3S2 and a molecular weight of 301.39 g/mol.
(E)-2-(1,1-dioxidothiomorpholino)-N'-(thiophen-2-ylmethylene)acetohydrazide (C11H15N3O3S2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (E)-2-(1,1-dioxidothiomorpholino)-N'-(thiophen-2-ylmethylene)acetohydrazide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H15N3O3S2 |
| Molecular Weight | 301.39 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 2 |
Related E Standards
- Methyl 2-(1,1-dioxidothiomorpholino)-3-phenylpropanoate (CAS 478040-49-2)
- 3-(1,1-Dioxidothiomorpholino)-3-(thiophen-2-yl)propanoic acid (CAS 885951-51-9)
- 4-(2-(1,1-Dioxidothiomorpholino)ethyl)benzenesulfonamide (CAS 866041-18-1)
- 2-(1,1-dioxidothiomorpholino)-3-phenylpropanoic acid (CAS 100610-68-2)
- N-(1,1-Dioxidothiomorpholino)-4-(trifluoromethyl)benzamide (CAS 677749-55-2)
- 2-(1,1-Dioxidothiomorpholino)-3-(1H-indol-3-yl)propanoic acid (CAS 477858-37-0)
- (E)-2-(1,1-dioxidothiomorpholino)-N'-(4-methoxybenzylidene)acetohydrazide (CAS 477889-89-7)
- N'-(2-(1,1-Dioxidothiomorpholino)acetyl)cyclopropanecarbohydrazide (CAS 860610-46-4)
Recommended Standards
- (5Z)-2-(Methylsulfanyl)-5-{[2-(1H-pyrazol-1-yl)phenyl]methylidene}-4,5-dihydro-1,3-thiazol-4-one (CAS 956792-01-1)
- 2-((2-(Diethylamino)-6-(phenylamino)pyrimidin-4-yl)amino)ethanol (CAS 88291-04-7)
- Tegaserod Impurity 1 (CAS 145158-71-0)
- 2-(Allylthio)-3-(pyridin-3-yl)thieno[3,2-d]pyrimidin-4(3H)-one (CAS 338779-50-3)
- N-benzyl-N-(3-(hydroxymethyl)oxetan-3-yl)-4-methylbenzenesulfonamide (CAS 2095219-05-7)
- 1-(2-Methoxyethyl)-1h-indazol-6-amine (CAS 938523-42-3)
- (3-Phenylbutyl)(prop-2-en-1-yl)amine hydrochloride (CAS 1240569-38-3)
- 1-(1-Ethyl-3-methyl-1h-pyrazol-4-yl)propan-1-one (CAS 1007518-77-5)
- Ethyl 5-Benzoxazolecarboxylate (CAS 1404370-64-4)
- 5-(4-Benzylpiperazin-1-yl)-2-nitrobenzaldehyde (CAS 1707581-08-5)
- 3-Bromo-2,5-dimethylpyridine 1-oxide (CAS 17117-20-3)
- Entrectinib Impurity 2 (CAS 1108745-33-0)
- (2R,3R,4R,5R)-2-Amino-4,5,6-trihydroxy-1-oxohexan-3-yl hydrogen sulfate (CAS 76330-20-6)
- Semaglutide impurity 257 (CAS CATO-C4X-2226257)
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