2-(2-(Trifluoromethyl)-1H-benzo[d]imidazol-1-yl)propanoic acid CAS 478030-59-0
| CAS No. | 478030-59-0 |
| Molecular Formula | C11H9F3N2O2 |
| Molecular Weight | 258.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(2-(Trifluoromethyl)-1H-benzo[d]imidazol-1-yl)propanoic acid.
2-(2-(Trifluoromethyl)-1H-benzo[d]imidazol-1-yl)propanoic acid (CAS 478030-59-0) is a high-purity analytical reference standard with the molecular formula C11H9F3N2O2 and a molecular weight of 258.20 g/mol.
Structurally, 2-(2-(Trifluoromethyl)-1H-benzo[d]imidazol-1-yl)propanoic acid (C11H9F3N2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 258.20 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-(2-(Trifluoromethyl)-1H-benzo[d]imidazol-1-yl)propanoic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H9F3N2O2 |
| Molecular Weight | 258.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Trifluoromethyl Standards
- 4-[3-(Trifluoromethyl)-3H-diazirin-3-yl]-benzenepropanoic acid (CAS 1002328-44-0)
- 5-Methyl-5-[3-(trifluoromethyl)phenyl]imidazolidine-2,4-dione (CAS 1052552-58-5)
- Ethyl 6-(trifluoromethyl)-1H-indazole-3-carboxylate (CAS 1053656-54-4)
- Ethyl 4-(trifluoromethyl)-1H-pyrrolo[3,2-c]pyridine-2-carboxylate (CAS 1060815-19-1)
- Ethyl 2-(trifluoromethyl)imidazo[1,2-a]pyridine-3-carboxylate (CAS 108438-46-6)
- 2-(6-(Trifluoromethyl)imidazo[1,2-a]pyridin-2-yl)acetohydrazide (CAS 1221792-29-5)
- Methyl 2-(6-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl)acetate (CAS 1221792-68-2)
- 2-{1-[5-(trifluoromethyl)pyridin-2-yl]-1H-1,2,3-triazol-4-yl}ethan-1-ol (CAS 1240526-47-9)
Recommended Standards
- 1-Cyclopropyl-5-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)-1H-tetrazole (CAS 321526-29-8)
- 2-(2-Oxo-5-(trifluoromethyl)pyridin-1(2h)-yl)-N-(prop-2-yn-1-yl)acetamide (CAS 923208-24-6)
- 1-[3-(trifluoromethyl)phenyl]hexahydropyrimidine-2,4-dione (CAS 491874-31-8)
- 2-(3-Cyanophenoxy)-N-(2,2,2-trifluoroethyl)acetamide (CAS 793677-47-1)
- 2-Bromo-6-(trifluoromethyl)pyridine-3-acetonitrile (CAS 1227512-33-5)
- N-(3-(3-hydroxyprop-1-yn-1-yl)-5-(trifluoromethyl)pyridin-2-yl)pivalamide (CAS 1346447-01-5)
- (E)-N-(2-(2-(1-(3-Bromophenyl)ethylidene)hydrazineyl)-2-oxo-1-(4-oxo-3,4-dihydrophthalazin-1-yl)ethyl)benzamide (CAS 916170-19-9)
- 2-Propoxyisoindoline-1,3-dione (CAS 51951-26-9)
- 3-(3,4-Dimethylphenyl)-2-methylpropanoic acid (CAS 1249807-44-0)
- 3-(Hydroxymethyl)-4-methylfuran-2,5-dione (CAS 245124-18-9)
- (E)-5-(benzo[d][1,3]dioxol-5-ylmethylene)-2-(methylthio)-3-(morpholinomethyl)-3,5-dihydro-4H-imidazol-4-one (CAS 865659-82-1)
- 5-Bromo-N-cyclopentyl-2-(trifluoromethyl)pyrimidin-4-amine (CAS 917895-58-0)
- 2-(1-Methylcyclopropyl)ethane-1-sulfonyl chloride (CAS 1803599-11-2)
- Serpent Peptide (CAS 823202-99-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com