1-(4-Fluorophenyl)-2-(2-(trifluoromethyl)-1H-benzo[d]imidazol-1-yl)ethan-1-one CAS 478030-60-3
| CAS No. | 478030-60-3 |
| Molecular Formula | C16H10F4N2O |
| Molecular Weight | 322.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-(4-Fluorophenyl)-2-(2-(trifluoromethyl)-1H-benzo[d]imidazol-1-yl)ethan-1-one is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
1-(4-Fluorophenyl)-2-(2-(trifluoromethyl)-1H-benzo[d]imidazol-1-yl)ethan-1-one (CAS 478030-60-3) is a high-purity analytical reference standard with the molecular formula C16H10F4N2O and a molecular weight of 322.26 g/mol.
The molecular framework of 1-(4-Fluorophenyl)-2-(2-(trifluoromethyl)-1H-benzo[d]imidazol-1-yl)ethan-1-one (C16H10F4N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 1-(4-Fluorophenyl)-2-(2-(trifluoromethyl)-1H-benzo[d]imidazol-1-yl)ethan-1-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H10F4N2O |
| Molecular Weight | 322.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Fluorophenyl Standards
- 5-{3-[(4-fluorophenyl)methyl]-1,2,4-oxadiazol-5-yl}-3-phenyl-1,2,4-oxadiazole (CAS 1775375-56-8)
- (r)-2-(2-Fluorophenyl)-1-((2-nitrophenyl)sulfonyl)aziridine (CAS 2089671-81-6)
- (s)-2-(2-Fluorophenyl)-1-((4-nitrophenyl)sulfonyl)aziridine (CAS 832117-96-1)
- 6-(4-Fluorophenyl)-1-[(3-fluorophenyl)methyl]-2-oxo-1,2-dihydropyridine-3-carbonitrile (CAS 252058-81-4)
- 3,6-bis(4-fluorophenyl)pyrazolo[1,5-a]pyrimidin-7-amine 685106-99-4 KS-000038J6 (CAS 685106-99-4)
- 1-(1-(4-Fluorophenyl)-5-oxopyrrolidin-3-yl)-3-morpholinourea (CAS 894020-77-0)
- 3-Ethyl-4-(2-fluorophenyl)-1H,2H,3H,4H,5H-indeno[1,2-d]pyrimidine-2,5-dione (CAS 861209-20-3)
- N-(2-(3-(1-(3-Fluorophenyl)-5-oxopyrrolidin-3-yl)ureido)ethyl)acetamide (CAS 894034-56-1)
Recommended Standards
- 1-((2,2-Difluorobenzo[d][1,3]dioxol-5-yl)methyl)-N-methyl-2-oxo-1,2-dihydropyridine-3-carboxamide (CAS 400083-03-6)
- 2,2,2-Trifluoro-1-(1-(2-fluorobenzyl)-1H-pyrrolo[2,3-b]pyridin-3-yl)ethan-1-one (CAS 860785-63-3)
- 7-Methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-6-yl trifluoromethanesulfonate (CAS 1454682-77-9)
- Methyl (R)-2-((S)-2,2-dimethyl-1,3-dioxolan-4-yl)-2-(((trifluoromethyl)sulfonyl)oxy)acetate (CAS 917017-18-6)
- (-)-Kurarinone (CAS 34981-26-5)
- Pyrrolidin-3-ylmethanolHCl (CAS 644971-22-2)
- Ethyl 2-((5-bromopyridin-2-yl)amino)-2-oxoacetate (Edoxaban Impurity) (CAS 141354-54-3)
- (4-Bromo-3-fluorophenethoxy)(tert-butyl)dimethylsilane (CAS 2758531-12-1)
- Morinidazole Impurity 33 (CAS CATO-C4X-219633)
- 5-(4-Chlorophenyl)pyrimidine (CAS 82525-17-5)
- Benzyl 4-(sulfanylmethyl)piperidine-1-carboxylate (CAS 1353970-98-5)
- 1-(Difluoromethyl)naphthalene-4-carboxaldehyde (CAS 1261871-64-0)
- 2-Amino-5-fluoropyridine-4-carboxamide (CAS 1803896-21-0)
- Neuropeptide Y (1-24) amide (human, rat) (CAS 131448-51-6)
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