3,3-Dimethyl-1-{3-[(4-nitrophenyl)methoxy]phenyl}azetidin-2-one CAS 478032-07-4
| CAS No. | 478032-07-4 |
| Molecular Formula | C18H18N2O4 |
| Molecular Weight | 326.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 326.35 g/mol gives 3,3-Dimethyl-1-{3-[(4-nitrophenyl)methoxy]phenyl}azetidin-2-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 3,3-Dimethyl-1-{3-[(4-nitrophenyl)methoxy]phenyl}azetidin-2-one (CAS 478032-07-4), a certified reference material (molecular formula C18H18N2O4, MW 326.35 g/mol) for analytical method development and quality control.
3,3-Dimethyl-1-{3-[(4-nitrophenyl)methoxy]phenyl}azetidin-2-one (C18H18N2O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3,3-Dimethyl-1-{3-[(4-nitrophenyl)methoxy]phenyl}azetidin-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H18N2O4 |
| Molecular Weight | 326.35 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 2 |
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- 2-[4-[(1H-1,2,4-Triazol-1-yl)methyl]phenyl]-1,3-dioxoisoindoline-5-carboxylic Acid (CAS 1092333-06-6)
- Liraglutide(8-31)TFA Salt (CAS CATO-C4X-19922)
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