5-(4-Chlorophenyl)-4-{2'-fluoro-4'-propyl-[1,1'-biphenyl]-4-yl}pyrimidine-2-thiol CAS 478032-55-2
| CAS No. | 478032-55-2 |
| Molecular Formula | C25H20ClFN2S |
| Molecular Weight | 434.96 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 5-(4-Chlorophenyl)-4-{2'-fluoro-4'-propyl-[1,1'-biphenyl]-4-yl}pyrimidine-2-thiol (CAS 478032-55-2), a certified reference material (molecular formula C25H20ClFN2S, MW 434.96 g/mol) for analytical method development and quality control.
The molecular framework of 5-(4-Chlorophenyl)-4-{2'-fluoro-4'-propyl-[1,1'-biphenyl]-4-yl}pyrimidine-2-thiol (C25H20ClFN2S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures 5-(4-Chlorophenyl)-4-{2'-fluoro-4'-propyl-[1,1'-biphenyl]-4-yl}pyrimidine-2-thiol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C25H20ClFN2S |
| Molecular Weight | 434.96 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chlorophenyl Standards
- 2-((5-(4-Chlorophenyl)-4-(p-tolyl)-4H-1,2,4-triazol-3-yl)thio)-N-phenylacetamide (CAS 443738-35-0)
- 2-((5-(4-Chlorophenyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)-N-(o-tolyl)acetamide (CAS 332922-54-0)
- 2-((5-(4-Chlorophenyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)-N-(p-tolyl)acetamide (CAS 332922-53-9)
- 2-(2-(2-Chlorophenyl)-4-phenylthiazol-5-yl)-N-(4-methoxyphenyl)acetamide (CAS 338957-27-0)
- 2-(2-(4-Chlorophenyl)-4-phenylthiazol-5-yl)-N-(4-methoxyphenyl)acetamide (CAS 339277-90-6)
- N-(3-chlorophenyl)-2-((4-phenyl-5-(p-tolyl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 332914-58-6)
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- 2-{[(2-chlorophenyl)methyl]sulfanyl}-4-(cyclohexylamino)-6-phenylpyrimidine-5-carbonitrile (CAS 303985-80-0)
Recommended Standards
- 2-Amino-5-(3-((4-(4-(2-(chloromethyl)-1,3-dioxolan-2-yl)butyl)phenyl)amino)propyl)-6-methylpyrimidin-4(3H)-one (CAS 2499-42-5)
- N-((4-allyl-5-(benzylthio)-4H-1,2,4-triazol-3-yl)methyl)-4-chlorobenzenesulfonamide (CAS 338422-29-0)
- Halcinonide Impurity N3 (CAS 2414269-43-3)
- Avatrombopag Impurity 98 (CAS CATO-C4X-223498)
- N-Methyl-N-(pyridin-2-yl)pyridin-2-amine (CAS 123368-97-8)
- 5-Amino-N-(2-hydroxyethyl)-2,3-dimethylbenzenesulfonamide (CAS 25797-78-8)
- 3α,7β-Di-O-acetyl Ursodeoxycholic Acid Methyl Ester (CAS 60384-30-7)
- [1,1′-Binaphthalen]-2-amine, 2′-(diphenylphosphino)-N,N-dimethyl-, (1R)- (CAS 216368-93-3)
- 2,5-Dimethoxy-3-nitrobenzoic acid (CAS 17894-26-7)
- N,N-Diethyl-2-((4-(phenylethynyl)pyrimidin-2-yl)oxy)ethanamine (CAS 87148-59-2)
- (2R,3S,4R)-2-(hydroxymethyl)-5-(4-methyl-8H-furo[2',3':4,5]pyrrolo[2,3-d]pyrimidin-8-yl)tetrahydrofuran-3,4-diol (CAS 2180983-36-0)
- N-((3-(4-chlorophenyl)isoxazol-5-yl)methyl)-2-morpholinoacetamide (CAS 478043-47-9)
- 4-(4-Bromobutoxy)benzaldehyde (CAS 72621-19-3)
- Allo-Thr5-Tirzepatide (CAS CATO-CPTD788934)
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