N'-[(1E)-(4-Chlorophenyl)methylidene]-4H,5H-naphtho[1,2-b]thiophene-2-carbohydrazide CAS 478033-51-1

Purity 97%+In StockPharmaceutical Standards
CAS No.478033-51-1
Molecular FormulaC20H15ClN2OS
Molecular Weight366.86 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N'-[(1E)-(4-Chlorophenyl)methylidene]-4H,5H-naphtho[1,2-b]thiophene-2-carbohydrazide CAS 478033-51-1 chemical structure

Description

The occurrence of N'-[(1E)-(4-Chlorophenyl)methylidene]-4H,5H-naphtho[1,2-b]thiophene-2-carbohydrazide is closely related to a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies N'-[(1E)-(4-Chlorophenyl)methylidene]-4H,5H-naphtho[1,2-b]thiophene-2-carbohydrazide (CAS 478033-51-1), a certified reference material (molecular formula C20H15ClN2OS, MW 366.86 g/mol) for analytical method development and quality control.

Owing to a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution, N'-[(1E)-(4-Chlorophenyl)methylidene]-4H,5H-naphtho[1,2-b]thiophene-2-carbohydrazide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 366.86 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures N'-[(1E)-(4-Chlorophenyl)methylidene]-4H,5H-naphtho[1,2-b]thiophene-2-carbohydrazide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC20H15ClN2OS
Molecular Weight366.86 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)14.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentCl-containing
Nitrogen Atoms2
Sulfur Atoms1

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