| CAS No. | 478033-53-3 |
| Molecular Formula | C21H18N2OS |
| Molecular Weight | 346.45 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
N'-[(1E)-(3-Methylphenyl)methylidene]-4H,5H-naphtho[1,2-b]thiophene-2-carbohydrazide (CAS 478033-53-3), molecular formula C21H18N2OS and molecular weight 346.45 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, N'-[(1E)-(3-Methylphenyl)methylidene]-4H,5H-naphtho[1,2-b]thiophene-2-carbohydrazide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 346.45 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures N'-[(1E)-(3-Methylphenyl)methylidene]-4H,5H-naphtho[1,2-b]thiophene-2-carbohydrazide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
| Molecular Formula | C21H18N2OS |
| Molecular Weight | 346.45 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |