1-(4-{[4-(4-chlorophenyl)piperazino]carbonyl}phenyl)-2-pyrrolidinone 478039-73-5 KS-000036IV CAS 478039-73-5
| CAS No. | 478039-73-5 |
| Molecular Formula | C21H22ClN3O2 |
| Molecular Weight | 383.87 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1-(4-{[4-(4-chlorophenyl)piperazino]carbonyl}phenyl)-2-pyrrolidinone 478039-73-5 KS-000036IV (C21H22ClN3O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
1-(4-{[4-(4-chlorophenyl)piperazino]carbonyl}phenyl)-2-pyrrolidinone 478039-73-5 KS-000036IV (CAS 478039-73-5), molecular formula C21H22ClN3O2 and molecular weight 383.87 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H22ClN3O2 |
| Molecular Weight | 383.87 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related chlorophenyl Standards
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Recommended Standards
- Pentyl 6-chloro-2-(4-methoxyphenyl)quinoline-4-carboxylate (CAS 355421-21-5)
- Prucalopride Impurity 21 (CAS 2636673-48-6)
- N-(4-Butylphenyl)-5-(3-chloro-4-methoxyphenyl)furan-2-carboxamide (CAS 853333-68-3)
- Prucalopride impurity 49 (CAS 566197-86-2)
- 3-(hydroxymethyl)oxetane-3-carbonitrile (CAS 1374657-44-9)
- 3-Methyl-N-(4-methylbenzyl)benzamide (CAS 349126-94-9)
- 3-Methoxy-1H-Indazole (CAS 1848-41-5)
- 5-(4-Methoxybenzamido)thiophene-2-carboxylic acid (CAS 1152992-43-2)
- 6-(3-Pyridinylcarbonyl)valerolactam (CAS 144751-22-4)
- rel-(1S,3R)-3-(Trifluoromethyl)cyclohexanol (CAS 23599-94-2)
- Cyclopropyl(6-cyclopropylpyridin-3-yl)methanone (CAS 56260-49-2)
- Ac-Tyr-Lys-NH? trifluoroacetate salt (CAS 270597-64-3)
- 2’-Hydroxy-5’-(trifluoromethoxy)acetophenone (CAS 146575-64-6)
- Semaglutide Impurity 148 (CAS CATO-C4X-2226148)
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