(2E)-3-[(4-Chlorophenyl)amino]-1-{3-[(2,4-dichlorophenyl)methoxy]phenyl}prop-2-en-1-one CAS 478040-22-1
| CAS No. | 478040-22-1 |
| Molecular Formula | C22H16Cl3NO2 |
| Molecular Weight | 432.73 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (2E)-3-[(4-Chlorophenyl)amino]-1-{3-[(2,4-dichlorophenyl)methoxy]phenyl}prop-2-en-1-one.
(2E)-3-[(4-Chlorophenyl)amino]-1-{3-[(2,4-dichlorophenyl)methoxy]phenyl}prop-2-en-1-one (CAS 478040-22-1), molecular formula C22H16Cl3NO2 and molecular weight 432.73 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, (2E)-3-[(4-Chlorophenyl)amino]-1-{3-[(2,4-dichlorophenyl)methoxy]phenyl}prop-2-en-1-one (C22H16Cl3NO2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 14.0, corresponding to approximately 14 ring(s) or double-bond equivalent(s). With a molecular weight of 432.73 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures (2E)-3-[(4-Chlorophenyl)amino]-1-{3-[(2,4-dichlorophenyl)methoxy]phenyl}prop-2-en-1-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H16Cl3NO2 |
| Molecular Weight | 432.73 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related E Standards
- (2E)-3-[(4-Chlorophenyl)amino]-1-{4-[(2,4-dichlorophenyl)methoxy]phenyl}prop-2-en-1-one (CAS 477889-40-0)
- 5-((4-Chlorophenyl)sulfinyl)-N-(3,4-dichlorophenyl)-1,2,3-thiadiazole-4-carboxamide (CAS 306976-91-0)
- 2-(2-Chlorophenyl)-4-[2,3-dichloro-4-(ethanesulfonyl)phenyl]-1,3-thiazole (CAS 672951-36-9)
- 2-(4-Chlorophenyl)-4-(2,3-dichloro-4-(ethylsulfonyl)phenyl)thiazole (CAS 672951-37-0)
- 5-[3-(4-Chlorophenyl)-1,2,4-oxadiazol-5-yl]-1-[(3,4-dichlorophenyl)methyl]-1,2-dihydropyridin-2-one (CAS 860649-89-4)
- N-[(4-Chlorophenyl)methyl]-5-oxo-2-(trifluoromethyl)-5H-chromeno[2,3-b]pyridine-3-carboxamide (CAS 241126-97-6)
- 1-((4-Chlorophenyl)sulfonyl)-N-(3-(trifluoromethyl)phenyl)pyrrolidine-2-carboxamide (CAS 317377-82-5)
- N-(4-chlorophenyl)-1-((3-(trifluoromethyl)phenyl)sulfonyl)pyrrolidine-2-carboxamide (CAS 317822-03-0)
Recommended Standards
- 1189685-87-7 N,N'-Di-(n-octyl-d17)-3,3'-dithiodipropionamide N-(1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecadeuteriooctyl)-3-[[3-(1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecadeuteriooctylamino)-3-oxopropyl]disulfanyl]propanamide (CAS 1189685-87-7)
- Tocopherol Impurity 32 (CAS CATO-C4X-119532)
- Tocopherol Impurity 25 (CAS 69371-91-1)
- 5-Chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-tosyl-1h-pyrrolo[2,3-b]pyridine (CAS 866546-11-4)
- 2-[(2,4,6-trimethylphenyl)amino]acetohydrazide (CAS 750624-66-9)
- 3,5-Dichloro-6-fluoro-N,N-dimethylpyrazin-2-amine (CAS 55233-63-1)
- tert-Butyl (2-chloro-5-formylpyridin-4-yl)carbamate (CAS 1956381-87-5)
- 5-((4-Chloro-3-methylphenoxy)methyl)-4-ethyl-4H-1,2,4-triazole-3-thiol (CAS 491647-37-1)
- tert-Butyl 4-(bromomethyl)-1,3-thiazol-2-ylcarbamate (CAS 1001419-35-7)
- Ethyl 4-formylbicyclo[2.2.2]octane-1-carboxylate (CAS 959958-67-9)
- Ethyl 3-(4-methoxybenzamido)benzoate (CAS 300827-74-1)
- (1S,3AR,4R,7aS)-1-((R)-1-hydroxy-2-methylpropyl)-3a-methyl-7-methyleneoctahydro-1H-inden-4-ol (CAS 640289-58-3)
- 2-(Methylthio)thiophene-3-carboxylic acid (CAS 71154-30-8)
- 551936-17-5 3JX85UOO24 AIM-102 UNII-3JX85UOO24 (4R)-4-(((2R)-2-Amino-3-cyclohexyl-propanoyl)amino)-5-(carboxymethylamino)-5-oxo-pentanoic acid D-Cyclohexylalanine-D-glutamic-glycine tripeptide Glycine, 3-cyclohexyl-D-alanyl-D-alpha-glutamyl- (CAS 551936-17-5)
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