5-Chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-tosyl-1h-pyrrolo[2,3-b]pyridine CAS 866546-11-4
| CAS No. | 866546-11-4 |
| Molecular Formula | C20H22BClN2O4S |
| Molecular Weight | 432.73 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution, 5-Chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-tosyl-1h-pyrrolo[2,3-b]pyridine is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 432.73 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies 5-Chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-tosyl-1h-pyrrolo[2,3-b]pyridine (CAS 866546-11-4), a certified reference material (molecular formula C20H22BClN2O4S, MW 432.73 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H22BClN2O4S |
| Molecular Weight | 432.73 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- (3Z)-3-{[(3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)amino]methylidene}-1,3-dihydro-2-benzofuran-1-one (CAS 337928-55-9)
- 7-Chloro-3-(3,4-dichlorophenyl)-9-oxo-9,10-dihydroacridin-1-yl acetate (CAS 144154-99-4)
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- 5-Chloro-2-iodo-1-tosyl-1H-pyrrolo[2,3-b]pyridine (CAS 1956322-68-1)
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Recommended Standards
- 5-((4-Chlorophenyl)sulfinyl)-N-(3,4-dichlorophenyl)-1,2,3-thiadiazole-4-carboxamide (CAS 306976-91-0)
- Isopropyl 3-(1H-indol-1-yl)propanoate (CAS 93982-57-1)
- (2E)-3-[(4-Chlorophenyl)amino]-1-{4-[(2,4-dichlorophenyl)methoxy]phenyl}prop-2-en-1-one (CAS 477889-40-0)
- 33312-01-5 3,3'-Dithiobis(N-octylpropionamide) Propanamide, 3,3'-dithiobis(N-octyl- N,N'-Bis-n-octyl-3,3'-dithiopropionamide EINECS 251-453-8 (CAS 33312-01-5)
- 5-Amino-3-bromopicolinonitrile (CAS 573762-88-6)
- n-(3,4-Dimethylbenzyl)-2-(pyrrolidin-1-yl)ethan-1-amine (CAS 1152693-52-1)
- 4-[(4'-methacryloyloxy)phenylazo]benzenesulfonicacid (CAS 1005792-99-3)
- 1-Benzyl-4-ethoxy-1h-indole-2-carboxylic acid (CAS 1240568-78-8)
- 1-Bromo-2,2,4-trimethylhexane (CAS 1476808-38-4)
- (2-Oxodihydrofuran-3(2H)-ylidene)methyl benzoate (CAS 67194-27-8)
- 5-Nitro-2H-benzo[b][1,4]oxazin-3(4H)-one (CAS 132522-81-7)
- Tert-butyl 3-(1-hydroxy-2-methylpropan-2-yl)azetidine-1-carboxylate (CAS 1375303-96-0)
- 3-Methoxy-N-(5-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl)benzamide (CAS 887885-99-6)
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