2-[5,7-Bis(trifluoromethyl)-1,8-naphthyridin-2-yl]-2-(4-bromophenyl)acetonitrile CAS 478043-29-7
| CAS No. | 478043-29-7 |
| Molecular Formula | C18H8BrF6N3 |
| Molecular Weight | 460.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
2-[5,7-Bis(trifluoromethyl)-1,8-naphthyridin-2-yl]-2-(4-bromophenyl)acetonitrile (CAS 478043-29-7), molecular formula C18H8BrF6N3 and molecular weight 460.17 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C18H8BrF6N3, 2-[5,7-Bis(trifluoromethyl)-1,8-naphthyridin-2-yl]-2-(4-bromophenyl)acetonitrile contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/bromine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 460.17 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H8BrF6N3 |
| Molecular Weight | 460.17 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 3 |
Related Bis Standards
- 5-Methyl-7-(3-(trifluoromethyl)phenyl)-N-(3,4,5-trimethoxyphenyl)imidazo[5,1-f][1,2,4]triazin-2-amine (CAS 774460-98-9)
- 2-{[3,5-di(trifluoromethyl)anilino]methylidene}-4,4,4-trifluoro-1-(2-thienyl)butane-1,3-dione (CAS 649578-87-0)
- Phenyl(3-(((3-(trifluoromethyl)benzyl)sulfonyl)methyl)benzofuran-2-yl)methanone (CAS 866017-29-0)
- 9,9-Bis(trifluoromethyl)-2,3,6,7-xanthenetetracarboxylic dianhydride (CAS 139162-14-4)
- N1-[3-(trifluoromethyl)phenyl]-2-{[5-(2,6-dichloro-4-pyridyl)-4-methyl-4H-1,2,4-triazol-3-yl]thio}acetamide (CAS 680216-62-0)
- 1-[5,7-Bis(trifluoromethyl)-1,8-naphthyridin-2-yl]-4-(4-chlorophenyl)-1H-pyrazol-5-amine (CAS 321522-22-9)
- Ethyl 5-(3-(trifluoromethyl)phenoxy)-3-(3-(trifluoromethyl)phenyl)-1,2,4-triazine-6-carboxylate (CAS 338957-80-5)
- 3-(Trifluoromethyl)phenyl N-{1-[(2,6-dichlorophenyl)methyl]-2-oxo-1,2-dihydropyridin-3-yl}carbamate (CAS 400084-82-4)
Recommended Standards
- Pinaverium Bromide Impurity 42 (CAS CATO-C4X-246742)
- 8-(4-Bromophenyl)-2,4-bis(trifluoromethyl)imidazo[1,2-a]1,8-naphthyridine (CAS 439093-95-5)
- 1,2-Dibromo-1,2-bis(3,4-dimethoxyphenyl)ethane (CAS 320576-20-3)
- 3-Chloro-2-((1-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-1,2,4-triazol-3-yl)thio)-5-(trifluoromethyl)pyridine (CAS 251307-13-8)
- 3-Amino-2,2-dimethylbutan-1-ol (CAS 51942-56-4)
- 1217640-14-6 N-Boc-N-methoxy-N-methyl-L-phenyl-d5-alaninamide (CAS 1217640-14-6)
- 4-Phenyl-2-(pyridin-2-yl)pentan-1-amine (CAS 1306606-05-2)
- LCZ-696 Impurity 33 (CAS CATO-C4X-169633)
- (3Z,6Z)-Dodeca-3,6-dien-1-ol (CAS 29125-78-8)
- Pemetrexed Impurity 72 TFA salt (CAS 884381-72-0（free base）)
- Dacomitinib Impurity 10 (CAS CATO-C4X-208610)
- 6-METHYL-2-PYRROLIDIN-2-YL-1H-BENZOIMIDAZOLE 6-methyl-2-(pyrrolidin-2-yl)-1H-benzo[d]imidazole 885278-00-2 (CAS 885278-00-2)
- 4-Ethoxy-6-methyl-2-(1H-pyrazol-1-yl)pyrimidine (CAS 114834-01-4)
- Insulin Glargine (CAS 160337-95-1)
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