1-(Thiophen-2-yl)-2-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)ethan-1-one CAS 478043-81-1
| CAS No. | 478043-81-1 |
| Molecular Formula | C17H17F3N2OS |
| Molecular Weight | 354.39 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(Thiophen-2-yl)-2-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)ethan-1-one.
CATO supplies 1-(Thiophen-2-yl)-2-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)ethan-1-one (CAS 478043-81-1), a certified reference material (molecular formula C17H17F3N2OS, MW 354.39 g/mol) for analytical method development and quality control.
1-(Thiophen-2-yl)-2-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)ethan-1-one (C17H17F3N2OS) contains a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(Thiophen-2-yl)-2-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)ethan-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H17F3N2OS |
| Molecular Weight | 354.39 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Thiophen Standards
- N-((1-(Thiophen-3-ylmethyl)piperidin-4-yl)methyl)benzofuran-2-carboxamide (CAS 1234904-89-2)
- N-((4-(Thiophen-2-yl)tetrahydro-2H-pyran-4-yl)methyl)quinoxaline-2-carboxamide (CAS 1207033-12-2)
- Methyl 4-((2-(3-(thiophen-2-yl)-1H-pyrazol-1-yl)ethyl)carbamoyl)benzoate (CAS 1448122-03-9)
- (5-(Thiophen-2-yl)isoxazol-3-yl)methyl 4-oxo-4H-chromene-2-carboxylate (CAS 946317-24-4)
- Ethyl 4-(4-(thiophen-2-yl)tetrahydro-2H-pyran-4-carbonyl)piperazine-1-carboxylate (CAS 877649-31-5)
- 1-Phenyl-2-((3-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)thio)ethan-1-one (CAS 868967-07-1)
- Thiophen-2-yl(7-(trifluoromethyl)-2,3,3a,4-tetrahydropyrrolo[1,2-a]quinoxalin-5(1H)-yl)methanone (CAS 861206-85-1)
- 3-(Thiophen-2-yl)-2-(1H-1,2,4-triazol-5-yl)-6-(trifluoromethyl)thieno[3,2-b]pyridine (CAS 477845-23-1)
Recommended Standards
- 1-(5-(4-(3-(Trifluoromethyl)phenyl)piperazin-1-yl)thiophen-2-yl)ethan-1-one (CAS 692287-80-2)
- 3,3-Dimethyl-1-({4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}methyl)azetidin-2-one (CAS 866018-73-7)
- 1-(2,3,5,6,8,9,11,12,14,15-Decahydrobenzo[b][1,4,7,10,13,16]hexaoxacyclooctadecin-18-yl)ethanone (CAS 41855-35-0)
- 4-(6-Dimethylamino-4-trifluoromethyl-pyridin-2-yl)-thiobenzoic acid S-ethyl ester (CAS 1983918-75-7)
- Rel-ethyl (1R,2R)-1-amino-2-ethylcyclopropane-1-carboxylate hydrochloride (CAS 717138-15-3)
- 2-Hydroxy-2-methyl-3-(6-methyl-2-oxo-1,2-dihydropyridin-1-yl)propanoic acid (CAS 1339200-28-0)
- N-Methyltryptamine HCl (CAS 942-27-8)
- 5-(Chloromethyl)pyrazolo[1,5-a]pyrimidin-7(4H)-one (CAS 1258651-02-3)
- Methyltriphenylphosphonium Iodide-13C (CAS 81826-67-7)
- 2-(4-Butylbenzamido)thiophene-3-carboxylic acid (CAS 1098375-06-4)
- 2-Amino-4-chloro-5-methoxybenzonitrile (CAS 1824059-40-6)
- 2-(4-Isopropylphenyl)pyrrolidine (CAS 881040-01-3)
- (R)-3-((tert-Butoxycarbonyl)amino)-2-(hydroxymethyl)propanoic acid (CAS 1190870-93-9)
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