(3Z)-3-{2-[3-(trifluoromethyl)phenyl]hydrazin-1-ylidene}-2,3-dihydro-1H-indole-2-thione CAS 478043-94-6
| CAS No. | 478043-94-6 |
| Molecular Formula | C15H10F3N3S |
| Molecular Weight | 321.32 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 321.32 g/mol gives (3Z)-3-{2-[3-(trifluoromethyl)phenyl]hydrazin-1-ylidene}-2,3-dihydro-1H-indole-2-thione distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
(3Z)-3-{2-[3-(trifluoromethyl)phenyl]hydrazin-1-ylidene}-2,3-dihydro-1H-indole-2-thione (CAS 478043-94-6) is a high-purity analytical reference standard with the molecular formula C15H10F3N3S and a molecular weight of 321.32 g/mol.
(3Z)-3-{2-[3-(trifluoromethyl)phenyl]hydrazin-1-ylidene}-2,3-dihydro-1H-indole-2-thione (C15H10F3N3S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (3Z)-3-{2-[3-(trifluoromethyl)phenyl]hydrazin-1-ylidene}-2,3-dihydro-1H-indole-2-thione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H10F3N3S |
| Molecular Weight | 321.32 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Z Standards
- N-(3-(Trifluoromethyl)phenyl)-1H-benzo[d]imidazole-2-carbothioamide (CAS 1105245-79-1)
- 4-(2-(4-(Trifluoromethyl)phenyl)thiazol-4-yl)phenol (CAS 1421263-30-0)
- (3Z)-3-({[3-(trifluoromethyl)phenyl]amino}methylidene)-1,3-dihydro-2-benzothiophen-1-one (CAS 338954-41-9)
- 5-Phenyl-2-(3-(trifluoromethyl)phenyl)thiazol-4-ol (CAS 924868-98-4)
- 1-Benzyl-4-(3-(trifluoromethyl)-pyridin-2-yl)piperazine 1043475-80-4 (CAS 1043475-80-4)
- 1-Benzyl-4-(4-(trifluoromethyl)-pyridin-3-yl)piperazine 1713160-39-4 (CAS 1713160-39-4)
- 1-Benzyl-4-(2-(trifluoromethyl)-pyridin-3-yl)piperazine (CAS 1774898-22-4)
- 1-Benzyl-4-(6-(trifluoromethyl)-pyridin-3-yl)piperazine (CAS 1779122-84-7)
Recommended Standards
- 2-(3,5-Dimethylphenoxy)-2,2-difluoro-N-(3-methoxyphenyl)acetamide (CAS 251097-71-9)
- Ethyl 2-(trifluoroacetamido)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate (CAS 171734-43-3)
- 2-Fluoro-5-(indolin-1-ylsulfonyl)benzoic acid (CAS 440343-72-6)
- 3-((2,4-Difluorophenyl)amino)-1-(3,4-dimethoxyphenyl)propan-1-one (CAS 763116-77-4)
- 53043-28-0 Austadiol 6H-2-Benzopyran-5-carboxaldehyde, 7,8-dihydro-7,8-dihydroxy-3,7-dimethyl-6-oxo-, (7R-trans)- (7R,8S)-7,8-Dihydro-7,8-dihydroxy-3,7-dimethyl-6-oxo-6H-2-benzopyran-5-carbaldehyde 5-18-04-00348 (Beilstein Handbook Reference) Austdiol Austidiol BRN 1383761 (7R-E)-7,8-Dihydro-7,8-dihydroxy-3,7-dimethyl-6-oxo-6H-2-benzopyran-5-carboxaldehyde NSC 159632 (CAS 53043-28-0)
- (2-Bromo-1-(sec-butoxy)ethyl)benzene (CAS 21269-99-8)
- 5-Fluoro-2-(2-methoxy-4-methylphenoxy)aniline (CAS 937596-47-9)
- 2'-Chloro-[1,1'-biphenyl]-3-carbaldehyde (CAS 675596-30-2)
- 4-(3-(4-Bromophenyl)propyl)morpholine (CAS 607744-36-5)
- Polaprezinc Impurity 29 (CAS CATO-C4X-182134)
- 4-(Iodomethyl)piperidine hydrochloride (CAS 1353976-20-1)
- Methyl 2-bromo-5-chloro-4-(trifluoromethyl)benzoate (CAS 2169152-40-1)
- 2-(5-Isopropyl-4,4-dimethyl-1,3,2-dioxaborolan-2-yl)-6-(trifluoromethyl)benzonitrile (CAS 883899-03-4)
- Semaglutide Impurity 115 (CAS CATO-C4X-2226115)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com