3-((2,4-Difluorophenyl)amino)-1-(3,4-dimethoxyphenyl)propan-1-one CAS 763116-77-4
| CAS No. | 763116-77-4 |
| Molecular Formula | C17H17F2NO3 |
| Molecular Weight | 321.32 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-((2,4-Difluorophenyl)amino)-1-(3,4-dimethoxyphenyl)propan-1-one.
3-((2,4-Difluorophenyl)amino)-1-(3,4-dimethoxyphenyl)propan-1-one (CAS 763116-77-4), molecular formula C17H17F2NO3 and molecular weight 321.32 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-((2,4-Difluorophenyl)amino)-1-(3,4-dimethoxyphenyl)propan-1-one (C17H17F2NO3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H17F2NO3 |
| Molecular Weight | 321.32 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
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- 1-[(2,6-difluorophenyl)methyl]-4-iodo-1H-1,2,3-triazole (CAS 1955540-09-6)
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- 1-Benzyl-2-(2,6-difluorophenyl)-1H-benzo[d]imidazole (CAS 199594-60-0)
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Recommended Standards
- 2-Fluoro-5-(indolin-1-ylsulfonyl)benzoic acid (CAS 440343-72-6)
- 5-Phenyl-2-(3-(trifluoromethyl)phenyl)thiazol-4-ol (CAS 924868-98-4)
- 2-(3,5-Dimethylphenoxy)-2,2-difluoro-N-(3-methoxyphenyl)acetamide (CAS 251097-71-9)
- Ethyl 2-(1,3-benzothiazol-2-ylsulfonyl)-2,2-difluoroacetate (CAS 477889-77-3)
- N-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)pentanamide (CAS 1628013-32-0)
- S-Butyrylthiocholine chloride (CAS 22026-63-7)
- 5-bromo-1-(4-fluorophenyl)-1H-pyrazole (CAS 1245149-36-3)
- Desmopressin Sulfur 0xidation Impurity (CAS CATO-C4X-221517)
- 1-Cyclohexyl-2-Fluoro-1-Propanone (CAS 21120-38-7)
- N-(2-((4-chlorobenzyl)thio)-2-methylpropyl)-4-methoxybenzenesulfonamide (CAS 343372-99-6)
- (5-Methylpyrrolidin-3-yl)methanol hydrochloride (CAS 1986336-97-3)
- 4-(4-Trifluoromethoxyphenyl)phenol (CAS 173025-79-1)
- n,n'-(Pentane-1,5-diyl)bis(2-chloroacetamide) (CAS 33619-33-9)
- Semaglutide impurity 275 (CAS CATO-C4X-2226275)
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