(3Z)-2-{[(4-chlorophenyl)methyl]sulfanyl}-3-{2-[3-(trifluoromethyl)phenyl]hydrazin-1-ylidene}-3H-indole CAS 478043-99-1
| CAS No. | 478043-99-1 |
| Molecular Formula | C22H15ClF3N3S |
| Molecular Weight | 445.89 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, (3Z)-2-{[(4-chlorophenyl)methyl]sulfanyl}-3-{2-[3-(trifluoromethyl)phenyl]hydrazin-1-ylidene}-3H-indole (C22H15ClF3N3S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 15.0, corresponding to approximately 15 ring(s) or double-bond equivalent(s). With a molecular weight of 445.89 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO supplies (3Z)-2-{[(4-chlorophenyl)methyl]sulfanyl}-3-{2-[3-(trifluoromethyl)phenyl]hydrazin-1-ylidene}-3H-indole (CAS 478043-99-1), a certified reference material (molecular formula C22H15ClF3N3S, MW 445.89 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (3Z)-2-{[(4-chlorophenyl)methyl]sulfanyl}-3-{2-[3-(trifluoromethyl)phenyl]hydrazin-1-ylidene}-3H-indole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H15ClF3N3S |
| Molecular Weight | 445.89 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Z Standards
- (3Z)-2-{[(2-chlorophenyl)methyl]sulfanyl}-3-{2-[3-(trifluoromethyl)phenyl]hydrazin-1-ylidene}-3H-indole (CAS 478044-94-9)
- (3Z)-2-{[(3-chlorophenyl)methyl]sulfanyl}-3-{2-[3-(trifluoromethyl)phenyl]hydrazin-1-ylidene}-3H-indole (CAS 478045-04-4)
- 4-((4-Chlorophenyl)sulfonyl)-6-(ethylsulfonyl)-3,4-dihydro-2H-benzo[b][1,4]oxazine-2-carboxylic acid (CAS 866051-02-7)
- 1-Benzyl-3-((3-chlorophenyl)sulfonyl)-6,7-difluoroquinolin-4(1H)-one (CAS 1326806-72-7)
- 1-(4-Chlorophenyl)-4-{2-[5-(trifluoromethyl)pyridin-2-yl]benzoyl}piperazine (CAS 1092345-91-9)
- (E)-4-(4-chlorophenyl)-2-methyl-6-(2-(((4-nitrobenzyl)oxy)imino)ethyl)pyridine-3,5-dicarbonitrile (CAS 303148-08-5)
- 3-{[(4-chlorophenyl)methyl](2-ethoxyphenyl)sulfamoyl}benzoic acid (CAS 929974-81-2)
- Methyl 2-(2-((5-(((4-chlorophenyl)amino)methyl)-4-methyl-4H-1,2,4-triazol-3-yl)thio)acetamido)benzoate (CAS 333314-29-7)
Recommended Standards
- 2-Oxo-2-(p-tolyl)ethyl 6-chloro-2-(4-methoxyphenyl)quinoline-4-carboxylate (CAS 355420-74-5)
- Osimertinib Impurity 116 (CAS CATO-C4X-2045116)
- Isopropyl 2-amino-4-(2-chloro-6-fluorophenyl)-5-oxo-4H,5H-thiochromeno[4,3-b]pyran-3-carboxylate (CAS 939894-25-4)
- [4-(Trifluoromethyl)phenyl]methyl N-{5-[(4-chlorophenyl)sulfanyl]-1,2,3-thiadiazol-4-yl}carbamate (CAS 400074-51-3)
- Methyl Methanethiosulfonate-d3 (CAS 55800-37-8)
- 6-chloro-N-methyl-pyrimidine-4-carboxamide (CAS 1215030-78-6)
- 2,4-Dichloro-6-(pyrrolidin-1-yl)pyrimidine (CAS 154117-92-7)
- N-(6-Aminopyridin-2-yl)-4'-cyano-[1,1'-biphenyl]-4-sulfonamide (CAS 857290-04-1)
- Furan-3-yl(2-methyl-[1,1'-biphenyl]-4-yl)methanol (CAS 1443306-47-5)
- Lintopride (CAS 107429-63-0)
- (4-Hydrazinylphenyl)(2-(hydroxymethyl)pyrrolidin-1-yl)methanone (CAS 1432792-66-9)
- 3-(2-((4-Chlorobenzyl)oxy)phenyl)-1-((2,5-dichlorophenyl)sulfonyl)-1H-pyrazole (CAS 477713-43-2)
- 2-Methyl-pyrrolidine-2-carboxylic acidmethylcarbamoylmethyl-amide hydrochloride (CAS 1361115-24-3)
- Semaglutide impurity 108 (CAS CATO-C4X-2226108)
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