(3Z)-2-{[(2-chlorophenyl)methyl]sulfanyl}-3-{2-[3-(trifluoromethyl)phenyl]hydrazin-1-ylidene}-3H-indole CAS 478044-94-9
| CAS No. | 478044-94-9 |
| Molecular Formula | C22H15ClF3N3S |
| Molecular Weight | 445.89 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), (3Z)-2-{[(2-chlorophenyl)methyl]sulfanyl}-3-{2-[3-(trifluoromethyl)phenyl]hydrazin-1-ylidene}-3H-indole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies (3Z)-2-{[(2-chlorophenyl)methyl]sulfanyl}-3-{2-[3-(trifluoromethyl)phenyl]hydrazin-1-ylidene}-3H-indole (CAS 478044-94-9), a certified reference material (molecular formula C22H15ClF3N3S, MW 445.89 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution, (3Z)-2-{[(2-chlorophenyl)methyl]sulfanyl}-3-{2-[3-(trifluoromethyl)phenyl]hydrazin-1-ylidene}-3H-indole is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 445.89 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C22H15ClF3N3S |
| Molecular Weight | 445.89 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Z Standards
- (3Z)-2-{[(3-chlorophenyl)methyl]sulfanyl}-3-{2-[3-(trifluoromethyl)phenyl]hydrazin-1-ylidene}-3H-indole (CAS 478045-04-4)
- (3Z)-2-{[(4-chlorophenyl)methyl]sulfanyl}-3-{2-[3-(trifluoromethyl)phenyl]hydrazin-1-ylidene}-3H-indole (CAS 478043-99-1)
- 4-((4-Chlorophenyl)sulfonyl)-6-(ethylsulfonyl)-3,4-dihydro-2H-benzo[b][1,4]oxazine-2-carboxylic acid (CAS 866051-02-7)
- 1-Benzyl-3-((3-chlorophenyl)sulfonyl)-6,7-difluoroquinolin-4(1H)-one (CAS 1326806-72-7)
- 1-(4-Chlorophenyl)-4-{2-[5-(trifluoromethyl)pyridin-2-yl]benzoyl}piperazine (CAS 1092345-91-9)
- (E)-4-(4-chlorophenyl)-2-methyl-6-(2-(((4-nitrobenzyl)oxy)imino)ethyl)pyridine-3,5-dicarbonitrile (CAS 303148-08-5)
- 3-{[(4-chlorophenyl)methyl](2-ethoxyphenyl)sulfamoyl}benzoic acid (CAS 929974-81-2)
- Methyl 2-(2-((5-(((4-chlorophenyl)amino)methyl)-4-methyl-4H-1,2,4-triazol-3-yl)thio)acetamido)benzoate (CAS 333314-29-7)
Recommended Standards
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- [4-(Trifluoromethyl)phenyl]methyl N-{5-[(4-chlorophenyl)sulfanyl]-1,2,3-thiadiazol-4-yl}carbamate (CAS 400074-51-3)
- [3-(Trifluoromethyl)phenyl]methyl N-{5-[(4-chlorophenyl)sulfanyl]-1,2,3-thiadiazol-4-yl}carbamate (CAS 400074-49-9)
- 2-Oxo-2-(p-tolyl)ethyl 6-chloro-2-(4-methoxyphenyl)quinoline-4-carboxylate (CAS 355420-74-5)
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