(E)-{[4-(benzyloxy)phenyl]methylidene}amino 4-(trifluoromethyl)benzoate CAS 478046-78-5
| CAS No. | 478046-78-5 |
| Molecular Formula | C22H16F3NO3 |
| Molecular Weight | 399.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(E)-{[4-(benzyloxy)phenyl]methylidene}amino 4-(trifluoromethyl)benzoate (CAS 478046-78-5) is a high-purity analytical reference standard with the molecular formula C22H16F3NO3 and a molecular weight of 399.36 g/mol.
(E)-{[4-(benzyloxy)phenyl]methylidene}amino 4-(trifluoromethyl)benzoate (C22H16F3NO3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (E)-{[4-(benzyloxy)phenyl]methylidene}amino 4-(trifluoromethyl)benzoate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H16F3NO3 |
| Molecular Weight | 399.36 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related E Standards
- (S)-4-(2-(((Benzyloxy)carbonyl)amino)-3-(tert-butoxy)-3-oxopropyl)benzoic acid (CAS 2007910-08-7)
- 2,4,6-Tris(benzyloxy)-1,3,5-triazine (CAS 7285-83-8)
- (S)-3-(4-(Benzyloxy)-2,6-dimethylphenyl)-2-((tert-butoxycarbonyl)amino)propanoic acid (CAS 945669-52-3)
- 2-{4-[4-(benzyloxy)phenyl]-1H-1,2,3-triazol-1-yl}-4-methyl-6-(2-methylpropyl)pyrimidine (CAS 861206-50-0)
- 1-(Benzyloxy)-3-((2-bromo-5-fluoro-4-nitrophenyl)amino)propan-2-ol (CAS 1431698-06-4)
- 2-(Benzyloxy)-1-bromo-3,5-bis(trifluoromethyl)benzene (CAS 2586126-89-6)
- 2-(Benzyloxy)-3,5-dibromo-4-methoxybenzaldehyde (CAS 35031-47-1)
- 4-(Benzyloxy)-2,3-dibromo-5-methoxybenzaldehyde (CAS 834907-51-6)
Recommended Standards
- (2E)-N-(4-Phenoxyphenyl)-3-[4-(trifluoromethoxy)phenyl]prop-2-enamide (CAS 882082-52-2)
- 2-((2,4-Dichlorobenzyl)thio)-3-ethyl-5,6-dimethylthieno[2,3-d]pyrimidin-4(3H)-one (CAS 587008-96-6)
- Methyl 3,3-dimethoxy-2-[2-[[6-(trifluoromethyl)pyridin-2-yl]oxymethyl]phenyl]propanoate (CAS 1448851-52-2)
- 2-((2,6-Dichlorobenzyl)thio)-3-ethyl-5,6-dimethylthieno[2,3-d]pyrimidin-4(3H)-one (CAS 578005-54-6)
- 2-(3-Fluorophenyl)pyrazolo[1,5-a]pyrazin-4(5H)-one (CAS 1338651-03-8)
- 2-(Piperidin-4-yl)ethane-1-sulfonamide (CAS 1179833-77-2)
- 1-(5-chloropyridin-2-yl)piperidine-4-carboxylic acid (CAS 953751-20-7)
- 1,4-dimethyl-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione (CAS 35252-00-7)
- 1,4-Di(1-pyrenyl)benzene (CAS 475460-77-6)
- Avatrombopag Impurity 16 (CAS CATO-C4X-223416)
- 4-Chloro-3-(piperidine-1-sulfonyl)benzoic acid (CAS 59210-74-1)
- 1-(3,4,5-Trimethoxy-phenyl)-1,2,3,4-tetrahydro-pyrrolo[1,2-a]pyrazine (CAS 73627-27-7)
- 4'-Cyano-biphenyl-3-carboxylic acid (CAS 149506-93-4)
- Allo-D-Ile17-Tirzepatide (CAS CATO-CPTD788962)
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