4-(4-(3-chlorobenzoyl)piperazin-1-yl)benzonitrile CAS 478046-92-3
| CAS No. | 478046-92-3 |
| Molecular Formula | C18H16ClN3O |
| Molecular Weight | 325.79 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 4-(4-(3-chlorobenzoyl)piperazin-1-yl)benzonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
4-(4-(3-chlorobenzoyl)piperazin-1-yl)benzonitrile (CAS 478046-92-3), molecular formula C18H16ClN3O and molecular weight 325.79 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-(4-(3-chlorobenzoyl)piperazin-1-yl)benzonitrile (C18H16ClN3O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C18H16ClN3O |
| Molecular Weight | 325.79 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related chlorobenzoyl Standards
- 4-(4-(4-Chlorobenzoyl)piperazin-1-yl)benzonitrile (CAS 478046-65-0)
- N-(4-Chlorobenzoyl)-6-quinolinecarbohydrazide (CAS 866018-93-1)
- 1-(4-Chlorobenzoyl)-3-(4-formylpiperazinyl)-thiourea (CAS 1987007-45-3)
- Ethyl 2-[1-(4-chlorobenzoyl)-3-oxopiperazin-2-yl]acetate (CAS 318469-63-5)
- 2-(3-(4-Chlorobenzoyl)-2-methylindolizin-1-yl)acetic acid (CAS 26466-68-2)
- 3-(4-Chlorobenzoyl)-1H,2H,3H,4H,5H,6H-benzo[f]isoquinoline (CAS 400074-06-8)
- 3-(4-Chlorobenzoyl)-4-[4-(propan-2-yl)phenyl]-1H-pyrrole (CAS 478031-47-9)
- 4-(3-Chlorobenzoyl)-1-oxa-4-azaspiro[4.5]decane-3-carboxylic acid (CAS 1008471-35-9)
Recommended Standards
- 4-((2-Chlorophenyl)amino)-2-(4-methylpiperazin-1-yl)-4-oxobutanoic acid (CAS 540763-74-4)
- 3-{[2-chloro-6-(1H-pyrrol-1-yl)phenyl]methyl}-1-phenylurea (CAS 866010-57-3)
- 4-(Morpholine-4-sulfonyl)benzene-1-sulfonyl chloride (CAS 465514-13-0)
- 3-(5-(4-Chlorophenyl)furan-2-yl)-N-phenylpropanamide (CAS 853311-43-0)
- 7-Chloro-N-(2,3-dimethylphenyl)quinazolin-4-amine (CAS 477860-65-4)
- 1-(Difluoromethyl)-2-fluoro-3-(trifluoromethyl)benzene (CAS 1214372-93-6)
- cis-2-Phenyl-pyrrolidine-3-carboxylic acid hydrochloride (CAS 1187927-05-4)
- (1S,5R)-8-azabicyclo[3.2.1]Octane-1-carboxylic acid (CAS 1218615-41-8)
- 2-[1-(4-fluorophenyl)-1h-pyrazol-3-yl]acetic acid (CAS 1354949-82-8)
- Pyridine-4-sulfonyl Fluoride (CAS 165053-24-7)
- 3-Methyl-5-(methylthio)-4-phenyl-4H-1,2,4-triazole (CAS 40279-27-4)
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- (S)-N-((1-Benzylpyrrolidin-2-yl)methyl)-2-chloroacetamide (CAS 1354015-95-4)
- Neuropeptide SF (human) (CAS 192387-39-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com