2,4-Bis(4-chlorophenyl)phthalazin-1(2H)-one CAS 478048-21-4

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2,4-Bis(4-chlorophenyl)phthalazin-1(2H)-one.

2,4-Bis(4-chlorophenyl)phthalazin-1(2H)-one (CAS 478048-21-4), molecular formula C20H12Cl2N2O and molecular weight 367.23 g/mol, is a CATO reference standard with documented purity and traceability.

Based on its molecular formula C20H12Cl2N2O, 2,4-Bis(4-chlorophenyl)phthalazin-1(2H)-one contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 367.23 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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