3-Chloro-1-(4-chlorobenzyl)-5-(morpholine-4-carbonyl)pyridin-2(1H)-one CAS 339024-79-2
| CAS No. | 339024-79-2 |
| Molecular Formula | C17H16Cl2N2O3 |
| Molecular Weight | 367.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-Chloro-1-(4-chlorobenzyl)-5-(morpholine-4-carbonyl)pyridin-2(1H)-one is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-Chloro-1-(4-chlorobenzyl)-5-(morpholine-4-carbonyl)pyridin-2(1H)-one (CAS 339024-79-2) is a high-purity analytical reference standard with the molecular formula C17H16Cl2N2O3 and a molecular weight of 367.23 g/mol.
The molecular framework of 3-Chloro-1-(4-chlorobenzyl)-5-(morpholine-4-carbonyl)pyridin-2(1H)-one (C17H16Cl2N2O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H16Cl2N2O3 |
| Molecular Weight | 367.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 4-((2-Chloro-6-fluorobenzylidene)amino)-3-(2-chlorophenyl)-1H-1,2,4-triazole-5(4H)-thione (CAS 478253-94-0)
- 4-((2-Chloro-6-fluorobenzylidene)amino)-3-(3-chlorophenyl)-1H-1,2,4-triazole-5(4H)-thione (CAS 478254-74-9)
- Bis(2-chloro-4-methylquinolin-6-yl)methane (CAS 500349-71-3)
- 2,2'-Bis[(5-chloro-2-hydroxyphenyl)methylene]-carbonic Dihydrazide (CAS 6638-52-4)
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Recommended Standards
- 2-Amino-4-(2,4-dichlorophenyl)-4H-benzo[h]chromene-3-carbonitrile (CAS 346436-68-8)
- 2,4-Bis(4-chlorophenyl)phthalazin-1(2H)-one (CAS 478048-21-4)
- 1-[(3,4-Dichlorophenyl)methyl]-5-(morpholine-4-carbonyl)-1,2-dihydropyridin-2-one (CAS 338781-26-3)
- 4-(2,4-Dichlorobenzoyl)-N-[(oxolan-2-yl)methyl]-1H-pyrrole-2-carboxamide (CAS 672949-69-8)
- (2E)-4-[(2-fluorophenyl)amino]-4-oxobut-2-enoic acid (CAS 63539-50-4)
- Methyl 2-amino-3-nitrobenzoate (CAS 57113-91-4)
- 3-Bromo-5-ethyl-1H-pyrazole (CAS 1015779-23-3)
- (S)-2-(3-Isobutyl-5-oxopiperazin-1-yl)acetic acid (CAS 1240589-55-2)
- N-methyl-3-phenyl-6-(trifluoromethyl)-1,2,4-triazin-5-amine (CAS 383148-46-7)
- Edoxaban Impurity 20 (CAS 1210348-34-7)
- 3-Ethyl-4-methylpyridine (CAS 529-21-5)
- Peldesine (CAS 133432-71-0)
- 4-Fluoro-N-(4-methoxybenzyl)aniline (CAS 80143-71-1)
- Des-Pro-Pro-Tirzepatide (CAS CATO-CPTD788696)
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