5-[(Benzenesulfonyl)methyl]-2-chloropyridine CAS 478048-53-2
| CAS No. | 478048-53-2 |
| Molecular Formula | C12H10ClNO2S |
| Molecular Weight | 267.73 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-[(Benzenesulfonyl)methyl]-2-chloropyridine (C12H10ClNO2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
5-[(Benzenesulfonyl)methyl]-2-chloropyridine (CAS 478048-53-2), molecular formula C12H10ClNO2S and molecular weight 267.73 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-[(Benzenesulfonyl)methyl]-2-chloropyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H10ClNO2S |
| Molecular Weight | 267.73 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Benzenesulfonyl Standards
- 23378-88-3 Benzenesulfonyl chloride, 3,5-dichloro-2-hydroxy- 3,5-Dichloro-2-hydroxybenzenesulphonyl chloride EINECS 245-619-9 (CAS 23378-88-3)
- 1-(benzenesulfonyl)cyclohexane-1-carboxylic acid (CAS 74254-66-3)
- 2-(benzenesulfonyl)ethane-1-sulfonyl chloride (CAS 64440-81-9)
- 2-[(Benzenesulfonyl)methyl]cyclohexane-1,3-dione (CAS 339098-50-9)
- 3-[(benzenesulfonyl)methyl]furan-2-carboxylic acid (CAS 260356-96-5)
- 5-[(benzenesulfonyl)methyl]furan-2-carboxylic acid (CAS 92959-89-2)
- 1-Benzenesulfonyl-piperidine-4-carboxylic acid (CAS 122891-92-3)
- (2E)-2-(Benzenesulfonyl)-3-phenylprop-2-enenitrile (CAS 129200-96-0)
Recommended Standards
- 5-(((3-Chlorophenyl)amino)methyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one (CAS 89665-77-0)
- 5-Chloro-2-((2,3-dihydrobenzofuran-5-yl)methyl)isothiazol-3(2H)-one (CAS 918107-66-1)
- 4-Chloro-N-phenylbenzenesulfonamide (CAS 7454-47-9)
- Dapsone Impurity 22 (CAS 64896-96-4)
- 1038702-50-9 AM86238 N-(2-(4-bromo-2-fluorophenoxy)ethyl)propan-2-amine (CAS 1038702-50-9)
- 2-Cyclobutylbutanoic acid (CAS 1508228-22-5)
- N-((Phenylselanyl)methyl)benzamide (CAS 110682-74-1)
- 8-Bromo-2-isopropylimidazo[1,2-a]pyridin-6-amine (CAS 1226000-18-5)
- 4-((2-(Dimethylamino)ethyl)(methyl)amino)benzaldehyde (CAS 28031-47-2)
- 4,6-Dimethyl-2-((piperidin-3-ylmethyl)thio)pyrimidine hydrochloride (CAS 1420800-76-5)
- 5,8-Difluoro-2-phenylquinolin-4-amine (CAS 1189106-37-3)
- CAS 84458-87-7 (CAS 84458-87-7)
- 3-Morpholinoquinoxaline-2-carboxylic acid (CAS 1211503-94-4)
- Copper Peptide ·2 acetate salt (CAS 130120-57-9)
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