1-(benzenesulfonyl)cyclohexane-1-carboxylic acid CAS 74254-66-3
| CAS No. | 74254-66-3 |
| Molecular Formula | C13H16O4S |
| Molecular Weight | 268.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
1-(benzenesulfonyl)cyclohexane-1-carboxylic acid (CAS 74254-66-3), molecular formula C13H16O4S and molecular weight 268.33 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(benzenesulfonyl)cyclohexane-1-carboxylic acid (C13H16O4S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), 1-(benzenesulfonyl)cyclohexane-1-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H16O4S |
| Molecular Weight | 268.33 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Sulfur Atoms | 1 |
Related benzenesulfonyl Standards
- 2-(benzenesulfonyl)ethane-1-sulfonyl chloride (CAS 64440-81-9)
- 5-[(Benzenesulfonyl)methyl]-2-chloropyridine (CAS 478048-53-2)
- 23378-88-3 Benzenesulfonyl chloride, 3,5-dichloro-2-hydroxy- 3,5-Dichloro-2-hydroxybenzenesulphonyl chloride EINECS 245-619-9 (CAS 23378-88-3)
- 1-Benzenesulfonyl-piperidine-4-carboxylic acid (CAS 122891-92-3)
- (2E)-2-(Benzenesulfonyl)-3-phenylprop-2-enenitrile (CAS 129200-96-0)
- 4-(benzenesulfonyl)oxane-4-carboxylic acid (CAS 1153968-63-8)
- 2-[(Benzenesulfonyl)methyl]cyclohexane-1,3-dione (CAS 339098-50-9)
- 3-[(benzenesulfonyl)methyl]furan-2-carboxylic acid (CAS 260356-96-5)
Recommended Standards
- 1-(4-(Piperazin-1-ylsulfonyl)phenyl)ethan-1-one (CAS 474711-09-6)
- 1-(Phenylsulfonyl)piperidine-4-carboxamide (CAS 304668-32-4)
- 1-(4-(Phenylsulfonyl)piperazin-1-yl)ethan-1-one (CAS 314728-83-1)
- 1-[4-(2-Benzothiazolylamino)phenyl]ethanone (CAS 74661-40-8)
- 4,5-Diphenyl-2-(p-tolyl)thiazole (CAS 120332-29-8)
- [(4-isopropyl-4H-1,2,4-triazol-3-yl)thio]acetic acid (CAS 923232-99-9)
- n-(2-Fluorophenyl)ethane-1-sulfonamide (CAS 544662-80-8)
- Inosine-5'-monophosphate disodium salt octahydrate (CAS 20813-76-7)
- (S)-2-Amino-2-(4-fluorophenyl)ethan-1,1-d2-1-ol (CAS 2878506-58-0)
- N-[2-(4-Bromobenzenesulfonyl)ethyl]-3-(trifluoromethyl)benzamide (CAS 338956-10-8)
- 2-Methyl-5-morpholinopentan-2-amine (CAS 933730-40-6)
- 2-Cyano-4-fluorobenzamide (CAS 1261643-35-9)
- (R)-(-)-1-(4-Chlorophenyl)ethyl isothiocyanate (CAS 737000-80-5)
- [a-Glu](Side chain transposition)- Semaglutide (CAS CATO-C4X-2226111)
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