5-Chloro-4-(4-methoxyphenoxy)-2-(4-methylphenyl)-2,3-dihydropyridazin-3-one CAS 478049-32-0
| CAS No. | 478049-32-0 |
| Molecular Formula | C18H15ClN2O3 |
| Molecular Weight | 342.78 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 5-Chloro-4-(4-methoxyphenoxy)-2-(4-methylphenyl)-2,3-dihydropyridazin-3-one (C18H15ClN2O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
5-Chloro-4-(4-methoxyphenoxy)-2-(4-methylphenyl)-2,3-dihydropyridazin-3-one (CAS 478049-32-0), molecular formula C18H15ClN2O3 and molecular weight 342.78 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-Chloro-4-(4-methoxyphenoxy)-2-(4-methylphenyl)-2,3-dihydropyridazin-3-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H15ClN2O3 |
| Molecular Weight | 342.78 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
- 6-(2-Chlorobenzyl)-3-((3-methoxyphenyl)amino)-1,2,4-triazin-5(4H)-one (CAS 535982-63-9)
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- 3-(4-((4-Chlorobenzyl)oxy)phenyl)-1H-pyrazole-5-carbohydrazide (CAS 763111-31-5)
- Benzotript (CAS 39544-74-6)
- 3-Bromo-5-(diphenylmethylene)furan-2(5H)-one (CAS 195390-04-6)
- 893756-56-4 2-Chloro-N-[5-chloro-2-(trifluoromethyl)phenyl]acetamide MFCD07365540 (CAS 893756-56-4)
- N-Boc-2-(benzylamino)acetaldehyde (CAS 136159-63-2)
- Apatinib impurity 4 (CAS 1376710-40-5)
- 4-(2-Phenyl-6-((phenylsulfinyl)methyl)pyrimidin-4-yl)morpholine (CAS 320421-35-0)
- 5-Nitro-1,3-dihydrobenzo[c]isothiazole 2,2-dioxide (CAS 111248-94-3)
- 2,4-Dichloro-5-methyl-5,7-dihydro-6H-pyrrolo[2,3-d]pyrimidin-6-one (CAS 1638767-98-2)
- 3-(((3-Hydroxypropyl)amino)methyl)-8-methylquinolin-2(1H)-one (CAS 462067-35-2)
- 1-(4'-(Tert-butyl)-[1,1'-biphenyl]-3-yl)-2,2,2-trifluoroethan-1-one (CAS 1443320-95-3)
- Semaglutide impurity 208 (CAS CATO-C4X-2226208)
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