1,1,1-Trifluoro-3-(piperidin-1-yl)propan-2-ol CAS 478050-22-5
| CAS No. | 478050-22-5 |
| Molecular Formula | C8H14F3NO |
| Molecular Weight | 197.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
1,1,1-Trifluoro-3-(piperidin-1-yl)propan-2-ol (CAS 478050-22-5), molecular formula C8H14F3NO and molecular weight 197.20 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1,1,1-Trifluoro-3-(piperidin-1-yl)propan-2-ol (C8H14F3NO) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures 1,1,1-Trifluoro-3-(piperidin-1-yl)propan-2-ol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H14F3NO |
| Molecular Weight | 197.20 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Trifluoro Standards
- 1,1,1-trifluoro-2-(4-piperidyl)propan-2-ol (CAS 1227068-37-2)
- 1,1,1-Trifluoro-2-(piperidin-2-yl)propan-2-ol (CAS 1258641-01-8)
- 2,2,2-Trifluoro-N-hexylacetamide (CAS 687-09-2)
- (1R)-2,2,2-trifluoro-1-(4-methyl-1,3-thiazol-2-yl)ethan-1-ol (CAS 1394051-21-8)
- 2,2,2-trifluoro-1-(4-methyl-1,3-thiazol-2-yl)ethan-1-ol (CAS 923215-80-9)
- Ethyl 4,4,4-trifluoro-3-(methylamino)but-2-enoate (CAS 121303-76-2)
- 3,3,3-Trifluoro-2-hydroxy-1-(pyrrolidin-1-yl)propan-1-one (CAS 125969-74-6)
- 2,2,2-Trifluoro-N-(2-hydroxycyclopentyl)acetamide (CAS 1864724-99-1)
Recommended Standards
- 1-(2,2,2-Trifluoroethyl)piperidine-4-methanol (CAS 831169-69-8)
- 2-(2,2,2-Trifluoroethoxy)cyclohexan-1-amine (CAS 929973-23-9)
- [1-methyl-4-(trifluoromethyl)-4-piperidyl]methanol (CAS 2227206-66-6)
- 2-(4-(Trifluoromethyl)piperidin-1-yl)ethan-1-ol (CAS 860343-96-0)
- 2-Methyl-10-phenyl-2,3-dihydroimidazo[2,1-b]quinazolin-5(10H)-one (CAS 57247-52-6)
- Ethyl 3-(1H-imidazol-5-yl)propanoate (CAS 52237-38-4)
- Ethyl trans-1-benzyl-4-(2,2,2-trifluoroethyl)pyrrolidine-3-carboxylate (CAS 1082745-51-4)
- 1-benzylpiperidine-3-carbaldehyde (CAS 145022-00-0)
- 1-{4-[(2-methylpiperidin-1-yl)methyl]phenyl}methanamine (CAS 926238-53-1)
- 8-(4-Bromo-3-fluorobenzyl)-1,4-dioxa-8-azaspiro[4.5]Decane (CAS 1704121-90-3)
- N-(2,5-dichloropyridin-4-yl)-N-ethyl-2,2,2-trifluoroacetamide (CAS 2380001-35-2)
- 3-(Piperazin-1-yl)tetrahydro-2h-thiopyran-3-carboxylic acid 1,1-dioxide (CAS 1404871-87-9)
- N-(3,5-Dimethylphenyl)-2-hydroxybenzamide (CAS 2819-59-2)
- Angiotensin III Antipeptide (CAS 133605-55-7)
Why CATO?
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