3-(1H-Pyrrol-1-yl)-N'-[(1Z)-(thiophen-2-yl)methylidene]thiophene-2-carbohydrazide CAS 478063-22-8
| CAS No. | 478063-22-8 |
| Molecular Formula | C14H11N3OS2 |
| Molecular Weight | 301.39 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-(1H-Pyrrol-1-yl)-N'-[(1Z)-(thiophen-2-yl)methylidene]thiophene-2-carbohydrazide.
CATO supplies 3-(1H-Pyrrol-1-yl)-N'-[(1Z)-(thiophen-2-yl)methylidene]thiophene-2-carbohydrazide (CAS 478063-22-8), a certified reference material (molecular formula C14H11N3OS2, MW 301.39 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, 3-(1H-Pyrrol-1-yl)-N'-[(1Z)-(thiophen-2-yl)methylidene]thiophene-2-carbohydrazide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 301.39 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H11N3OS2 |
| Molecular Weight | 301.39 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 2 |
Related H Standards
- 2-(((1H-Pyrrol-2-yl)methylene)hydrazono)-1,2-diphenylethanone (CAS 201161-08-2)
- 1-(1H-Pyrrol-3-yl)propan-1-one (CAS 1193-61-9)
- (4-(1H-Pyrrol-1-yl)pyridin-2-yl)(3,4-dihydroquinolin-1(2H)-yl)methanone (CAS 1421473-53-1)
- 1-(4-(6-(1H-Pyrrol-1-yl)pyridazin-3-yl)piperazin-1-yl)butan-1-one (CAS 1421474-50-1)
- 2-(2-(1H-Pyrrol-1-yl)thiazol-4-yl)-N-(pyridin-2-ylmethyl)acetamide (CAS 1172307-70-8)
- 2-(3-(1H-pyrrol-1-yl)phenyl)-4-methylthiazole-5-carbohydrazide (CAS 262589-42-4)
- 4-(1H-Pyrrol-1-yl)-N-(2-(thiophen-3-yl)ethyl)benzamide (CAS 1286710-60-8)
- (2-(1H-Pyrrol-1-yl)thiazol-4-yl)(indolin-1-yl)methanone (CAS 1207054-33-8)
Recommended Standards
- 2-(Prop-2-en-1-ylsulfanyl)-3-(pyridin-2-yl)-3H,4H-thieno[3,2-d]pyrimidin-4-one (CAS 338780-25-9)
- 4-(((3-Methylthiophen-2-yl)methylene)amino)-3-(pyridin-2-yl)-1H-1,2,4-triazole-5(4H)-thione (CAS 613248-17-2)
- 2-(Allylthio)-3-(pyridin-3-yl)thieno[3,2-d]pyrimidin-4(3H)-one (CAS 338779-50-3)
- 4-(((5-Methylthiophen-2-yl)methylene)amino)-3-(pyridin-2-yl)-1H-1,2,4-triazole-5(4H)-thione (CAS 497823-98-0)
- (4Z)-4-{[(5-chloro-2-hydroxyphenyl)amino]methylidene}-1-methyl-3-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-5-one (CAS 320425-04-5)
- 3-prop-2-ynylspiro[3.4]octan-3-ol (CAS 2104019-96-5)
- 1-Octyl-4-vinylbenzene (CAS 46745-66-8)
- 1-[(dimethylcarbamoyl)methyl]-3-(trifluoromethyl)-1h-pyrazole-5-carboxylic acid (CAS 1245808-55-2)
- 6-Amino-3-methyl-5-(naphthalen-1-yl)-1-phenylpyridazin-4(1H)-one (CAS 89313-94-0)
- tert-Butyl 3-(3-bromo-2,2-difluoropropanoyl)pyrrolidine-1-carboxylate (CAS 2766367-06-8)
- 2-Chloro-5-(cyclohexylcarbamoyl)benzeneboronic acid (CAS 1449132-56-2)
- Diethyl thiazole-2,4-dicarboxylate (CAS 40235-67-4)
- 3-(7-Chloro-2-methyl-2,3-dihydro-1,4-benzoxazepin-4(5H)-yl)propanoic acid (CAS 1119452-95-7)
- Tau Peptide (301-315) trifluoroacetate salt (CAS 330456-48-9)
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