4-(((5-Methylthiophen-2-yl)methylene)amino)-3-(pyridin-2-yl)-1H-1,2,4-triazole-5(4H)-thione CAS 497823-98-0
| CAS No. | 497823-98-0 |
| Molecular Formula | C13H11N5S2 |
| Molecular Weight | 301.39 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 301.39 g/mol gives 4-(((5-Methylthiophen-2-yl)methylene)amino)-3-(pyridin-2-yl)-1H-1,2,4-triazole-5(4H)-thione distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
4-(((5-Methylthiophen-2-yl)methylene)amino)-3-(pyridin-2-yl)-1H-1,2,4-triazole-5(4H)-thione (CAS 497823-98-0) is a high-purity analytical reference standard with the molecular formula C13H11N5S2 and a molecular weight of 301.39 g/mol.
The molecular framework of 4-(((5-Methylthiophen-2-yl)methylene)amino)-3-(pyridin-2-yl)-1H-1,2,4-triazole-5(4H)-thione (C13H11N5S2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-(((5-Methylthiophen-2-yl)methylene)amino)-3-(pyridin-2-yl)-1H-1,2,4-triazole-5(4H)-thione under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H11N5S2 |
| Molecular Weight | 301.39 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 2 |
Related Methylthiophen Standards
- 4-(((3-Methylthiophen-2-yl)methylene)amino)-3-(pyridin-2-yl)-1H-1,2,4-triazole-5(4H)-thione (CAS 613248-17-2)
- 6-(5-Methylthiophen-2-yl)-1-(propan-2-yl)-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid (CAS 924232-60-0)
- 2-[(4-methylthiophen-3-yl)methyl]-1,3-dioxo-2,3-dihydro-1H-isoindole-5-carboxylic acid (CAS 1511848-76-2)
- 2,5-Bis(5-methylthiophen-2-yl)benzene-1,4-diamine (CAS 2422197-69-9)
- 6-Ethyl-2-(5-methylthiophen-2-yl)quinoline-4-carboxylic acid (CAS 588711-29-9)
- (5-Methylthiophen-2-yl)(4-phenoxyphenyl)methanol (CAS 944685-02-3)
- 1'-((5-Methylthiophen-2-yl)methyl)spiro[indoline-3,4'-piperidin]-2-one (CAS 1609899-41-3)
- N-[1-(5-methylthiophen-2-yl)propan-2-yl]thieno[2,3-d]pyrimidin-4-amine (CAS 1379051-17-8)
Recommended Standards
- 4-Phenyl-5-((pyrimidin-2-ylthio)methyl)-4H-1,2,4-triazole-3-thiol (CAS 872696-21-4)
- 3-(1H-Pyrrol-1-yl)-N'-[(1Z)-(thiophen-2-yl)methylidene]thiophene-2-carbohydrazide (CAS 478063-22-8)
- 5-[(4-phenoxyphenyl)amino]-1,3,4-thiadiazole-2-thiol (CAS 380431-13-0)
- 2-(Prop-2-en-1-ylsulfanyl)-3-(pyridin-2-yl)-3H,4H-thieno[3,2-d]pyrimidin-4-one (CAS 338780-25-9)
- 1,1-Dicyclopropyl-N-methylmethanamine oxalate (CAS 2089651-35-2)
- 5-Chloro-2-methoxy-3-nitrophenyl benzoate (CAS 1221792-84-2)
- Methyl (E)-N-(4-fluorophenyl)formimidate (CAS 1283244-51-8)
- methyl 4-bromo-2-(prop-2-yn-1-yloxy)benzoate (CAS 1312610-35-7)
- 3,10-Diazabicyclo[4.3.1]decan-4-one (CAS 1208711-11-8)
- 4-(Pyrrolidin-1-ylmethyl)benzaldehyde (CAS 650628-72-1)
- 2-(tert-Butoxy)-3-cyclopropoxy-6-isopropylpyridine (CAS 1243395-85-8)
- 5-Ethyl-1-(4-methylphenyl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1017399-25-5)
- Bucladesine Impurity 2 (CAS 70253-67-7)
- Semaglutide impurity 71 (CAS CATO-C4X-222671)
Why CATO?
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