3-(2,4-Dichlorobenzyl)-4-hydroxy-1-(2-(naphthalen-1-ylamino)ethyl)pyridin-2(1H)-one CAS 478063-83-1
| CAS No. | 478063-83-1 |
| Molecular Formula | C24H20Cl2N2O2 |
| Molecular Weight | 439.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 439.33 g/mol gives 3-(2,4-Dichlorobenzyl)-4-hydroxy-1-(2-(naphthalen-1-ylamino)ethyl)pyridin-2(1H)-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 3-(2,4-Dichlorobenzyl)-4-hydroxy-1-(2-(naphthalen-1-ylamino)ethyl)pyridin-2(1H)-one (CAS 478063-83-1), a certified reference material (molecular formula C24H20Cl2N2O2, MW 439.33 g/mol) for analytical method development and quality control.
The molecular framework of 3-(2,4-Dichlorobenzyl)-4-hydroxy-1-(2-(naphthalen-1-ylamino)ethyl)pyridin-2(1H)-one (C24H20Cl2N2O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-(2,4-Dichlorobenzyl)-4-hydroxy-1-(2-(naphthalen-1-ylamino)ethyl)pyridin-2(1H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H20Cl2N2O2 |
| Molecular Weight | 439.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Dichlorobenzyl Standards
- 1-(2,6-Dichlorobenzyl)-3-methyl-4-(4-methylbenzoyl)-3,4-dihydroquinoxalin-2(1H)-one (CAS 317822-42-7)
- 2-((2,6-Dichlorobenzyl)thio)-5-methoxy-4-((4-methoxyphenyl)thio)pyrimidine (CAS 338955-92-3)
- 3-((3,4-Dichlorobenzyl)thio)-1-(p-tolyl)-5,6,7,8-tetrahydroisoquinoline-4-carbonitrile (CAS 607696-36-6)
- (Z)-2-(4-(3-(2,6-dichlorobenzyl)-2-methyl-4-oxopyridin-1(4H)-yl)phenyl)-3-(dimethylamino)acrylonitrile (CAS 400074-55-7)
- 3-((2,6-Dichlorobenzyl)sulfonyl)-N-(p-tolyl)thiophene-2-carboxamide (CAS 251097-78-6)
- N-(4-((2,4-dichlorobenzyl)thio)phenyl)-2-((1-methyl-1H-tetrazol-5-yl)thio)acetamide (CAS 303091-89-6)
- 3-(((2,4-Dichlorobenzyl)sulfinyl)methyl)-4-methyl-5-((4-methylbenzyl)thio)-4H-1,2,4-triazole (CAS 344272-10-2)
- 1-(2,4-Dichlorobenzyl)-6-oxo-N-(3-(trifluoromethyl)phenyl)-1,6-dihydropyridine-3-carboxamide (CAS 242797-39-3)
Recommended Standards
- 2-(4-Benzoylphenyl)-2-(2,4-dichlorophenyl)-N-[(1E)-(dimethylamino)methylidene]acetamide (CAS 338965-62-1)
- 3-Amino-N-(3-bromo-4-methylphenyl)-6-(pyridin-4-yl)thieno[2,3-b]pyridine-2-carboxamide (CAS 626226-18-4)
- 1-[(3,4-Dichlorophenyl)methyl]-3,4-bis(4-methoxyphenyl)-1H-pyrazole (CAS 956756-11-9)
- 3-Amino-N-(4-bromo-3-methylphenyl)-6-(pyridin-4-yl)thieno[2,3-b]pyridine-2-carboxamide (CAS 445267-33-4)
- 1-Methyl-5-(trifluoromethyl)-1H-pyrazol-3-amine hydrochloride (CAS 1431962-50-3)
- N1-(2-Aminoethyl)-N1-isopropyl-N4,N4-dimethylcyclohexane-1,4-diamine (CAS 1353972-31-2)
- (R)-1-(1-(1-(Tert-butoxycarbonyl)piperidin-4-yl)ethyl)-2-methyl-1H-indole-3-carboxylic acid (CAS 1659300-60-3)
- 3-(Aminomethyl)-4,4,4-trifluoro-3-hydroxybutanoic acid (CAS 929975-06-4)
- 1-(1-Ethyl-3-methyl-1h-pyrazol-4-yl)-4,4-difluorobutane-1,3-dione (CAS 1005629-65-1)
- Trimetazidine Impurity 30 (CAS CATO-C4X-180330)
- (2S)-3-(4-aminophenyl)-2-hydroxy-propanoic acid (CAS 66592-67-4)
- (2S,3S)-2-amino-N-(3-methoxypropyl)-3-methylpentanamide (CAS 1867638-86-5)
- 4-((3-Amino-1H-1,2,4-triazol-1-yl)methyl)benzoic acid (CAS 869945-43-7)
- Fibrinogen-Binding Peptide (CAS 137235-80-4)
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