2-Chloro-2,2-difluoro-1-(1H-indol-3-yl)ethan-1-one CAS 478065-02-0

Purity 97%+In StockPharmaceutical Standards
CAS No.478065-02-0
Molecular FormulaC10H6ClF2NO
Molecular Weight229.61 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Chloro-2,2-difluoro-1-(1H-indol-3-yl)ethan-1-one CAS 478065-02-0 chemical structure

Description

CATO manufactures 2-Chloro-2,2-difluoro-1-(1H-indol-3-yl)ethan-1-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

CATO supplies 2-Chloro-2,2-difluoro-1-(1H-indol-3-yl)ethan-1-one (CAS 478065-02-0), a certified reference material (molecular formula C10H6ClF2NO, MW 229.61 g/mol) for analytical method development and quality control.

Based on its molecular formula C10H6ClF2NO, 2-Chloro-2,2-difluoro-1-(1H-indol-3-yl)ethan-1-one contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 229.61 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

Physical & Chemical Properties

Molecular FormulaC10H6ClF2NO
Molecular Weight229.61 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF/Cl-containing
Nitrogen Atoms1

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