(E)-{1-[3-(4-chlorophenyl)-1,2-oxazol-5-yl]ethylidene}amino benzoate CAS 478066-78-3

Purity 97%+In StockPharmaceutical Standards
CAS No.478066-78-3
Molecular FormulaC18H13ClN2O3
Molecular Weight340.76 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(E)-{1-[3-(4-chlorophenyl)-1,2-oxazol-5-yl]ethylidene}amino benzoate CAS 478066-78-3 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

(E)-{1-[3-(4-chlorophenyl)-1,2-oxazol-5-yl]ethylidene}amino benzoate (CAS 478066-78-3) is a high-purity analytical reference standard with the molecular formula C18H13ClN2O3 and a molecular weight of 340.76 g/mol.

Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, (E)-{1-[3-(4-chlorophenyl)-1,2-oxazol-5-yl]ethylidene}amino benzoate is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 340.76 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

As a certified reference material (CRM), (E)-{1-[3-(4-chlorophenyl)-1,2-oxazol-5-yl]ethylidene}amino benzoate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC18H13ClN2O3
Molecular Weight340.76 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)13.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentCl-containing
Nitrogen Atoms2

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