(Z)-3-amino-3-(4-(3-(trifluoromethyl)phenoxy)phenyl)acrylonitrile CAS 478068-18-7
| CAS No. | 478068-18-7 |
| Molecular Formula | C16H11F3N2O |
| Molecular Weight | 304.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(Z)-3-amino-3-(4-(3-(trifluoromethyl)phenoxy)phenyl)acrylonitrile (CAS 478068-18-7), molecular formula C16H11F3N2O and molecular weight 304.27 g/mol, is a CATO reference standard with documented purity and traceability.
(Z)-3-amino-3-(4-(3-(trifluoromethyl)phenoxy)phenyl)acrylonitrile (C16H11F3N2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (Z)-3-amino-3-(4-(3-(trifluoromethyl)phenoxy)phenyl)acrylonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H11F3N2O |
| Molecular Weight | 304.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
- (S,R)-5-CF3-Pyox-In (CAS 2412578-71-1)
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- (R,S)-5-CF3-Pyox-In (CAS 2097333-76-9)
- 1-Hydroxy-9,10-dioxo-9,10-dihydroanthracene-2-sulfonic acid (CAS 56670-83-8)
- 2-Cyclohexyl-3-oxoisoindoline-4-carboxylic acid (CAS 626205-17-2)
- 5-Amino-2-propionamidobenzoic acid (CAS 1488889-41-3)
- 4-[(5Z)-5-[(4-Methoxyphenyl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]butanoic acid (CAS 380569-12-0)
- Haloperidol impurity 24 (CAS 3110-52-9)
- Diethyl 2,3-dihydroxysuccinate (CAS 408332-88-7)
- 4-(chloromethyl)-2-methyl-1H-pyrrolo[2,3-b]pyridine (CAS 1638763-98-0)
- Benzyl N-(4-nitrophenyl)carbamate (CAS 53821-12-8)
- 3-Bromo-2-fluoro-5-nitroaniline (CAS 1309833-32-6)
- (1S,3R)-3-(trifluoromethyl)cyclohexane-1-carboxylic acid (CAS 1821707-08-7)
- Hippocampal Cholinergic Neurostimulating Peptide (CAS 140158-49-2)
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