| CAS No. | 3110-52-9 |
| Molecular Formula | C10H10ClFO |
| Molecular Weight | 200.64 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Compared with other compounds in its class, the molecular weight of 200.64 g/mol gives Haloperidol impurity 24 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Haloperidol impurity 24 (CAS 3110-52-9) is a certified pharmaceutical impurity reference standard with the molecular formula C10H10ClFO and a molecular weight of 200.64 g/mol.
Owing to a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system, Haloperidol impurity 24 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 200.64 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Haloperidol impurity 24 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
| Molecular Formula | C10H10ClFO |
| Molecular Weight | 200.64 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/Cl-containing |