2-[3-(1H-Pyrrol-1-yl)thiophen-2-yl]-5-({[3-(trifluoromethyl)phenyl]methyl}sulfanyl)-1,3,4-oxadiazole CAS 478077-33-7
| CAS No. | 478077-33-7 |
| Molecular Formula | C18H12F3N3OS2 |
| Molecular Weight | 407.43 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-[3-(1H-Pyrrol-1-yl)thiophen-2-yl]-5-({[3-(trifluoromethyl)phenyl]methyl}sulfanyl)-1,3,4-oxadiazole (C18H12F3N3OS2) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies 2-[3-(1H-Pyrrol-1-yl)thiophen-2-yl]-5-({[3-(trifluoromethyl)phenyl]methyl}sulfanyl)-1,3,4-oxadiazole (CAS 478077-33-7), a certified reference material (molecular formula C18H12F3N3OS2, MW 407.43 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-[3-(1H-Pyrrol-1-yl)thiophen-2-yl]-5-({[3-(trifluoromethyl)phenyl]methyl}sulfanyl)-1,3,4-oxadiazole under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H12F3N3OS2 |
| Molecular Weight | 407.43 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 2 |
Related H Standards
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Recommended Standards
- 2-(4-(2,4-Dimethylphenyl)piperazin-1-yl)-N-(4-(trifluoromethoxy)phenyl)acetamide (CAS 882082-37-3)
- Risdiplam Impurity 3 (CAS CATO-C4X-30123)
- (3S,4S)-4-(4-(Benzyloxy)phenyl)-3-((S)-1,2-dihydroxyethyl)-1-(4-fluorophenyl)azetidin-2-one (CAS 221349-56-0)
- Methyl (R)-N-(bis(4-methoxyphenyl)methyl)serinate S,S-dioxide (CAS 1212136-00-9)
- 6-(Pyrrolidin-1-yl)-[1,2,4]triazolo[4,3-b]pyridazine-3-carboxylic acid (CAS 1211487-42-1)
- Diethyl(methanesulfonyloxymethyl)phosphonate (CAS 114108-84-8)
- (4,5-Dioxo-4,5-dihydro-1H-pyrazol-3-yl)carbamic acid (CAS 859955-10-5)
- 4-Ethyl-3-(trifluoromethyl)-1,2-oxazol-5-amine (CAS 166964-41-6)
- 2-Demethyl Colchicine (CAS 102491-80-5)
- 1-(2-Thienyl)-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine (CAS 865546-35-6)
- 4,5-Dihydroisothiazole 1,1-dioxide (CAS 881652-45-5)
- Tirzepatide Impurity 11 TFA salt (CAS CATO-C4X-324011)
- 1-(3-Bromoprop-1-en-1-yl)-4-nitrobenzene (CAS 75059-04-0)
- Semaglutide Impurity 246 (CAS CATO-C4X-2226246)
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