1-(2-Chloro-4-fluorophenoxy)-3-(4-fluorobenzenesulfonyl)propan-2-ol CAS 478079-85-5
| CAS No. | 478079-85-5 |
| Molecular Formula | C15H13ClF2O4S |
| Molecular Weight | 362.78 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1-(2-Chloro-4-fluorophenoxy)-3-(4-fluorobenzenesulfonyl)propan-2-ol (C15H13ClF2O4S) is characterized by a flavonoid core, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
1-(2-Chloro-4-fluorophenoxy)-3-(4-fluorobenzenesulfonyl)propan-2-ol (CAS 478079-85-5) is a high-purity analytical reference standard with the molecular formula C15H13ClF2O4S and a molecular weight of 362.78 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-(2-Chloro-4-fluorophenoxy)-3-(4-fluorobenzenesulfonyl)propan-2-ol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H13ClF2O4S |
| Molecular Weight | 362.78 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Sulfur Atoms | 1 |
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