2-(4-Chlorophenyl)-4-{6-methyl-[1,2,4]triazolo[3,2-b][1,3]thiazol-5-yl}-1,3-thiazole CAS 478080-31-8
| CAS No. | 478080-31-8 |
| Molecular Formula | C14H9ClN4S2 |
| Molecular Weight | 332.83 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-(4-Chlorophenyl)-4-{6-methyl-[1,2,4]triazolo[3,2-b][1,3]thiazol-5-yl}-1,3-thiazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 2-(4-Chlorophenyl)-4-{6-methyl-[1,2,4]triazolo[3,2-b][1,3]thiazol-5-yl}-1,3-thiazole (CAS 478080-31-8), a certified reference material (molecular formula C14H9ClN4S2, MW 332.83 g/mol) for analytical method development and quality control.
The molecular framework of 2-(4-Chlorophenyl)-4-{6-methyl-[1,2,4]triazolo[3,2-b][1,3]thiazol-5-yl}-1,3-thiazole (C14H9ClN4S2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H9ClN4S2 |
| Molecular Weight | 332.83 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 2 |
Related Chlorophenyl Standards
- 3-(4-Chlorophenyl)-1,5-diphenyl-4,5-dihydro-1H-pyrazole (CAS 10180-02-6)
- 1-(4-Chlorophenyl)-N-((2-morpholinopyrimidin-5-yl)methyl)ethan-1-amine (CAS 1280981-01-2)
- 1-(2-Chlorophenyl)-3-(5-hydroxy-3-phenylpentyl)urea (CAS 1795301-96-0)
- 3-(5-(4-Chlorophenyl)furan-2-yl)-1-(4-methylpiperazin-1-yl)propan-1-one (CAS 853312-37-5)
- N-(4-Chlorophenyl)-2-{1-[5-(cyanomethyl)-2-thienyl]ethylidene}-1-hydrazinecarboxamide (CAS 866142-46-3)
- N-(4-chlorophenyl)-4-(pyridin-2-yl)piperazine-1-carbothioamide (CAS 431886-32-7)
- N-(4-chlorophenyl)-2-(3-oxo-3,4-dihydro-2H-benzo[b][1,4]thiazin-2-yl)acetamide (CAS 132858-26-5)
- 5-(4-Chlorophenyl)-4-tosyl-1H-pyrazole (CAS 140614-07-9)
Recommended Standards
- 2-(4-Chlorobenzyl)-3-(p-tolyl)-2H-indazole (CAS 872681-97-5)
- 4-Chloro-N-((4-methyl-5-(methylthio)-4H-1,2,4-triazol-3-yl)methyl)benzenesulfonamide (CAS 338421-48-0)
- 2-(3-Chlorobenzyl)-3-(p-tolyl)-2H-indazole (CAS 872681-99-7)
- 4-Chloro-N-[(4-ethyl-5-sulfanyl-4H-1,2,4-triazol-3-yl)methyl]benzene-1-sulfonamide (CAS 338421-80-0)
- 5,5-Dimethyl-7-oxabicyclo[4.1.0]heptan-2-one (CAS 1074-26-6)
- 6-Chloro-2-cyclopropyl-7-methyl-7H-purine (CAS 1713713-54-2)
- 3-Isopropylquinazoline-2,4(1H,3H)-dione (CAS 5943-91-9)
- 3-(4-Bromophenyl)-1-(p-tolyl)propan-1-one (CAS 898760-99-1)
- 7-(2-Chlorophenyl)-7-oxoheptanenitrile (CAS 898767-80-1)
- Latanoprost EP Impurity H-D4 (CAS 1224443-47-3)
- 6-Chloro-2-(2-chlorophenyl)-3-hydroxy-3,4-dihydroquinazolin-4-one (CAS 338412-45-6)
- Dacomitinib Impurity 10 (CAS CATO-C4X-208610)
- 2-Methyl-6-nitro-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazine-2-carboxylic acid (CAS 154365-44-3)
- Liraglutide Impurity 17 TFA Salt (CAS CATO-C4X-199217)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com