4-(4-Chloro-2-methylphenoxy)-5-methanesulfonyl-2-phenylpyrimidine CAS 478080-90-9
| CAS No. | 478080-90-9 |
| Molecular Formula | C18H15ClN2O3S |
| Molecular Weight | 374.84 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 374.84 g/mol gives 4-(4-Chloro-2-methylphenoxy)-5-methanesulfonyl-2-phenylpyrimidine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
4-(4-Chloro-2-methylphenoxy)-5-methanesulfonyl-2-phenylpyrimidine (CAS 478080-90-9) is a high-purity analytical reference standard with the molecular formula C18H15ClN2O3S and a molecular weight of 374.84 g/mol.
Structurally, 4-(4-Chloro-2-methylphenoxy)-5-methanesulfonyl-2-phenylpyrimidine (C18H15ClN2O3S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 374.84 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-(4-Chloro-2-methylphenoxy)-5-methanesulfonyl-2-phenylpyrimidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H15ClN2O3S |
| Molecular Weight | 374.84 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
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Recommended Standards
- 3-(5-Chlorothiophen-2-yl)-N'-(2-ethoxybenzylidene)-1H-pyrazole-5-carbohydrazide (CAS 303106-95-8)
- 5-(2-Chlorophenyl)-4-((2,4-dimethoxybenzylidene)amino)-4H-1,2,4-triazole-3-thiol (CAS 352329-58-9)
- 3-(4-Chlorobenzyl)-4-oxo-2-(phenylimino)-1,3-thiazinane-6-carboxylic acid (CAS 312512-86-0)
- Etoricoxib Impurity 10 (CAS 349536-41-0)
- 4-(4-(4-Bromophenyl)-5-((3-fluorobenzyl)thio)-4H-1,2,4-triazol-3-yl)pyridine (CAS 477329-86-5)
- Tris(4-(dimethylamino)phenyl)phosphine oxide (CAS 807-20-5)
- 2-((Dimethylamino)methylene)-N1,N3-bis(3-(trifluoromethyl)phenyl)malonamide (CAS 245039-15-0)
- U-54494ahydrochloride (CAS 112465-94-8)
- 1-(o-Tolyl)butan-1-ol (CAS 5407-62-5)
- 2-(((2-Bromoethyl)amino)methyl)cyclohexan-1-one hydrobromide (CAS 479192-79-5)
- 2-Chloro-4,5-bis(1,1,2,2,2-pentafluoroethyl)pyridine (CAS 1246466-42-1)
- Ethyl 5-cyano-6-((2-methoxybenzyl)amino)-2-phenylnicotinate (CAS 477866-14-1)
- Mirabegron Impurity 85 (CAS CATO-C4X-103285)
- Semaglutide impurity 43 (CAS CATO-C4X-222643)
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