1-(4-Chloro-3-methoxyphenyl)-4-[(4-methoxyphenyl)methylidene]-2-sulfanyl-4,5-dihydro-1H-imidazol-5-one CAS 721407-95-0
| CAS No. | 721407-95-0 |
| Molecular Formula | C18H15ClN2O3S |
| Molecular Weight | 374.84 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 1-(4-Chloro-3-methoxyphenyl)-4-[(4-methoxyphenyl)methylidene]-2-sulfanyl-4,5-dihydro-1H-imidazol-5-one (CAS 721407-95-0), a certified reference material (molecular formula C18H15ClN2O3S, MW 374.84 g/mol) for analytical method development and quality control.
1-(4-Chloro-3-methoxyphenyl)-4-[(4-methoxyphenyl)methylidene]-2-sulfanyl-4,5-dihydro-1H-imidazol-5-one (C18H15ClN2O3S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H15ClN2O3S |
| Molecular Weight | 374.84 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
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Recommended Standards
- Methyl 5-(2-aminothiazol-4-yl)-2-((2-chlorobenzyl)oxy)benzoate (CAS 1416347-35-7)
- 2-((4-Allyl-5-(furan-2-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(3-chlorophenyl)acetamide (CAS 578697-46-8)
- Methyl 5-(2-aminothiazol-4-yl)-2-((3-chlorobenzyl)oxy)benzoate (CAS 1416344-47-2)
- 2-((4-Allyl-5-(furan-2-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(4-chlorophenyl)acetamide (CAS 575470-78-9)
- pyrrolidine-3,4-dicarboxamide (CAS 1989671-65-9)
- 2-{[4-(pyridin-2-yl)piperazin-1-yl]methyl}aniline (CAS 1016750-36-9)
- sec-Butyl 2-(morpholin-2-yl)acetate (CAS 1520916-07-7)
- (R)-2-amino-3-(benzylthio)-N-(naphthalen-2-yl)propanamide (CAS 7436-63-7)
- 1-(methylsulfanyl)cyclopropane-1-carbonitrile (CAS 35120-11-7)
- 2-(2-Ethoxyphenyl)-4-methyl-6-(phenylamino)quinazoline-5,8-dione (CAS 61416-85-1)
- Ethyl 2-(4-(4-bromophenylsulfonyl)piperazinoacetate (CAS 1022353-79-2)
- 2-(Thiophen-2-yl)pyrimidine-5-carbonitrile (CAS 926921-77-9)
- Yttrium(III) nitrate tetrahydrate (CAS 13773-69-8)
- Semaglutide impurity 99 (CAS CATO-C4X-222699)
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