5-(Benzenesulfonyl)-2-phenyl-4-{[3-(trifluoromethyl)phenyl]sulfanyl}pyrimidine CAS 478081-00-4
| CAS No. | 478081-00-4 |
| Molecular Formula | C23H15F3N2O2S2 |
| Molecular Weight | 472.50 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-(Benzenesulfonyl)-2-phenyl-4-{[3-(trifluoromethyl)phenyl]sulfanyl}pyrimidine (C23H15F3N2O2S2) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
5-(Benzenesulfonyl)-2-phenyl-4-{[3-(trifluoromethyl)phenyl]sulfanyl}pyrimidine (CAS 478081-00-4), molecular formula C23H15F3N2O2S2 and molecular weight 472.50 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-(Benzenesulfonyl)-2-phenyl-4-{[3-(trifluoromethyl)phenyl]sulfanyl}pyrimidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C23H15F3N2O2S2 |
| Molecular Weight | 472.50 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Related Benzenesulfonyl Standards
- 4-(Benzenesulfonyl)-3-{4-[(4-chlorophenyl)methoxy]-3-methoxyphenyl}-2-methyl-1,2-oxazolidine (CAS 339110-42-8)
- 3-(Benzenesulfonyl)-4,6-dimethylpyridin-2-yl 2,4,6-trichlorobenzoate (CAS 400082-20-4)
- 5-(Benzenesulfonyl)-4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-2-(pyridin-4-yl)pyrimidine (CAS 866017-81-4)
- (E)-[2-(Benzenesulfonyl)-2-(6-chloropyridin-3-yl)ethylidene][(2,3-dichlorophenyl)methoxy]amine (CAS 478048-61-2)
- 4-(Benzenesulfonyl)-3-{3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl}-2-methyl-1,2-oxazolidine (CAS 339110-46-2)
- 5-(Benzenesulfonyl)-4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-2-(thiophen-2-yl)pyrimidine (CAS 866017-83-6)
- N-(Benzenesulfonyl)-N-(3-cyano-5-phenylfuran-2-yl)benzenesulfonamide (CAS 478045-63-5)
- 3-(Benzenesulfonyl)-7-chloro-N-(4-ethylphenyl)-[1,2,3]triazolo[1,5-a]quinazolin-5-amine (CAS 904578-68-3)
Recommended Standards
- 3-(2-(((4-Carbamoylphenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoic acid (Dabigatran Impurity) (CAS 2417628-79-4)
- N-(6-Amino-9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-8-yl)-N-(9H-fluoren-2-yl)acetamide (CAS 86637-09-4)
- 1-(6-(Cyclopentylamino)-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-2-yl)-N-ethyl-1H-pyrazole-4-carboxamide (CAS 920974-60-3)
- tert-Butyl 7-bromo-5-chloro-4-iodo-1-oxoisoindoline-2-carboxylate (CAS 2628352-04-3)
- 5-methyl-5-(2-methylphenyl)imidazolidine-2,4-dione (CAS 88807-84-5)
- L-Erythrose (~0.1 M solution in water) (CAS 533-49-3)
- 2-Isopropylbenzaldehyde (CAS 6502-22-3)
- 6-tert-Butylpyridine-3-sulfonyl chloride (CAS 1037241-40-9)
- 3-(sec-Butylamino)-1H-pyrazol-5(4H)-one (CAS 57338-45-1)
- 3-Methyl-5-(4-methylphenyl)-1,2,4-oxadiazole (CAS 122503-24-6)
- Tert-butyl 2-amino-8-oxa-5-azaspiro[3.5]Nonane-5-carboxylate (CAS 1251019-55-2)
- 5-Bromo-2-(4-fluorophenyl)pyridine (CAS 463336-07-4)
- 3-Bromo-4-chloro-6-methoxyquinoline (CAS 1203579-29-6)
- Semaglutide Impurity 177 (CAS CATO-C4X-2226177)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com