5-(Benzenesulfonyl)-4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-2-(pyridin-4-yl)pyrimidine CAS 866017-81-4
| CAS No. | 866017-81-4 |
| Molecular Formula | C25H18N4O2S2 |
| Molecular Weight | 470.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 5-(Benzenesulfonyl)-4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-2-(pyridin-4-yl)pyrimidine (C25H18N4O2S2) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 19.0, corresponding to approximately 19 ring(s) or double-bond equivalent(s). With a molecular weight of 470.57 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
5-(Benzenesulfonyl)-4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-2-(pyridin-4-yl)pyrimidine (CAS 866017-81-4), molecular formula C25H18N4O2S2 and molecular weight 470.57 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C25H18N4O2S2 |
| Molecular Weight | 470.57 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 19.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 2 |
Related Benzenesulfonyl Standards
- 3-(Benzenesulfonyl)-4,6-dimethylpyridin-2-yl 2,4,6-trichlorobenzoate (CAS 400082-20-4)
- (E)-[2-(Benzenesulfonyl)-2-(6-chloropyridin-3-yl)ethylidene][(2,3-dichlorophenyl)methoxy]amine (CAS 478048-61-2)
- 4-(Benzenesulfonyl)-3-{3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl}-2-methyl-1,2-oxazolidine (CAS 339110-46-2)
- 5-(Benzenesulfonyl)-2-phenyl-4-{[3-(trifluoromethyl)phenyl]sulfanyl}pyrimidine (CAS 478081-00-4)
- 4-(Benzenesulfonyl)-3-{4-[(4-chlorophenyl)methoxy]-3-methoxyphenyl}-2-methyl-1,2-oxazolidine (CAS 339110-42-8)
- 5-(Benzenesulfonyl)-4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-2-(thiophen-2-yl)pyrimidine (CAS 866017-83-6)
- N-(Benzenesulfonyl)-N-(3-cyano-5-phenylfuran-2-yl)benzenesulfonamide (CAS 478045-63-5)
- 3-(Benzenesulfonyl)-7-chloro-N-(4-ethylphenyl)-[1,2,3]triazolo[1,5-a]quinazolin-5-amine (CAS 904578-68-3)
Recommended Standards
- 4-Methyl-2-phenyl-5-(5-(phenylsulfonyl)-2-(pyridin-3-yl)pyrimidin-4-yl)thiazole (CAS 866017-82-5)
- N-Boc-2(S)-2-amino-3-{1-[(2,4,6-trimethylphenyl)sulfonyl]-1H-indol-3-yl}propanal (CAS 1026493-36-6)
- (S)-N-(4-(Acridin-9-ylamino)phenyl)-2,6-diamino-N-(2-amino-2-oxoethyl)hexanamide (CAS 83209-81-8)
- Dicyclohexyl(3,3′,5′,6-tetramethoxy[1,1′-biphenyl]-2-yl)phosphine (CAS 1262046-31-0)
- 2-((5-Benzyl-4-ethyl-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 482643-39-0)
- [1,3-Bis(2,6-diisopropylphenyl)imidazol-2-ylidene][1,3-divinyl-1,1,3,3-tetramethyldisiloxane]palladium(0) (CAS 478019-87-3)
- 2-((1H-1,2,3-triazol-5-yl)thio)ethan-1-amine hydrochloride (CAS 1262771-37-8)
- 6-(4-Methoxyphenyl)-2-methylpyrimidin-4-amine (CAS 88614-06-6)
- N1-benzyl-N1-ethyl-2-methylpropane-1,2-diamine (CAS 1082554-22-0)
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- 2-Aninyl Thiophenol (CAS 16078-95-8)
- 2-Bromo-N-cyclobutylaniline (CAS 1248313-08-7)
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- Semaglutide impurity 44 (CAS CATO-C4X-222644)
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