(Z)-3-amino-3-[4-(4-chloro-3-fluorophenoxy)phenyl]-2-propenenitrile CAS 478081-39-9
| CAS No. | 478081-39-9 |
| Molecular Formula | C15H10ClFN2O |
| Molecular Weight | 288.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies (Z)-3-amino-3-[4-(4-chloro-3-fluorophenoxy)phenyl]-2-propenenitrile (CAS 478081-39-9), a certified reference material (molecular formula C15H10ClFN2O, MW 288.70 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, (Z)-3-amino-3-[4-(4-chloro-3-fluorophenoxy)phenyl]-2-propenenitrile is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 288.70 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H10ClFN2O |
| Molecular Weight | 288.70 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Z Standards
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Recommended Standards
- Diethyl 2-(2-chloro-6-fluorophenyl)malonate (CAS 190521-88-1)
- 1-(7-Chloro-2-(4-fluorophenyl)pyrazolo[1,5-a]pyridin-3-yl)ethanone (CAS 437384-08-2)
- 2-Chloro-4-(2-fluorophenyl)-7,8-dihydro-5H-pyrano[4,3-b]pyridine-3-carbonitrile (CAS 1707609-93-5)
- 2-(1-(4-Chlorophenyl)-1H-pyrazol-5-yl)-5-fluorophenol (CAS 876950-42-4)
- Methyl 2-(1H-pyrazol-1-yl)propanoate (CAS 100554-34-5)
- (S)-2-(2,6-Dichlorobenzamido)succinic acid (CAS 1786734-56-2)
- Methyl 1-Methyl-5-indolecarboxylate (CAS 128742-76-7)
- tert-Butyl 4-amino-9-oxa-2-azaspiro[5.5]undecane-2-carboxylate (CAS 2095410-40-3)
- 5-Methyl-2-((trimethylsilyl)methyl)pyridine (CAS 158588-03-5)
- 1-(3-Isopropyl-1-methyl-1H-pyrazol-5-yl)-N-((1-propyl-1H-pyrazol-5-yl)methyl)methanamine hydrochloride (CAS 1856078-33-5)
- 20882-04-6 (2-((2-Methyl-1-oxoallyl)oxy)ethyl) hydrogen succinate Butanedioic acid, 1-(2-((2-methyl-1-oxo-2-propen-1-yl)oxy)ethyl) ester Butanedioic acid, mono(2-((2-methyl-1-oxo-2-propenyl)oxy)ethyl) ester EINECS 244-096-4 (CAS 20882-04-6)
- tert-Butyl 1-formyl-5-azaspiro[2.4]heptane-5-carboxylate (CAS 1780561-46-7)
- N,N'-Bis(salicylidene)ethylenediaminonickel(II) (CAS 14167-20-5)
- Semaglutide impurity 26 (CAS CATO-C4X-222626)
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