2,6-Dibromo-4-iodopyridin-3-ol CAS 478148-75-3
| CAS No. | 478148-75-3 |
| Molecular Formula | C5H2Br2INO |
| Molecular Weight | 378.79 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2,6-Dibromo-4-iodopyridin-3-ol (CAS 478148-75-3), molecular formula C5H2Br2INO and molecular weight 378.79 g/mol, is a CATO reference standard with documented purity and traceability.
2,6-Dibromo-4-iodopyridin-3-ol (C5H2Br2INO) contains an amide group, a hydroxyl group, an ether linkage, bromine/iodine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2,6-Dibromo-4-iodopyridin-3-ol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H2Br2INO |
| Molecular Weight | 378.79 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Br/I-containing |
| Nitrogen Atoms | 1 |
Related Dibromo Standards
- 2,6-Dibromo-5-iodopyridin-3-ol (CAS 1105675-63-5)
- 5,6-Dibromo-3-iodopyrazin-2-amine (CAS 1823904-74-0)
- 3,6-Dibromo-5-iodopyrazin-2-amine (CAS 1823960-91-3)
- 2,3-Dibromo-6-(bromomethyl)naphthalene (CAS 132112-62-0)
- 3,5-Dibromo-6H-anthra[1,9-cd]isoxazol-6-one (CAS 82840-40-2)
- 4,5-Dibromo-N-(2-fluorophenyl)thiophene-2-carboxamide (CAS 1011426-77-9)
- N-(3,5-dibromo-2-methoxybenzyl)-1-(tetrahydrofuran-2-yl)methanamine (CAS 893604-20-1)
- 3,5-Dibromo-4-(chlorosulfonyl)benzoic acid (CAS 1375474-74-0)
Recommended Standards
- 1-[3-(4-Chlorobenzenesulfonyl)propoxy]-3-(trifluoromethyl)benzene (CAS 338792-65-7)
- 4-Chloro-N-(4-hydroxynaphthalen-1-yl)-3-nitrobenzenesulfonamide (CAS 420092-79-1)
- Selumetinib Impurity 1 (CAS CATO-C4X-30531)
- (5-((4-Chlorophenyl)thio)-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)methyl propionate (CAS 955962-82-0)
- 3-(Isobutylthio)dihydrofuran-2,5-dione (CAS 164597-79-9)
- 1-(3-Pyridylmethyl)piperazine trihydrochloride (CAS 333992-77-1)
- 6-Bromo-3-iodo-4-methoxyquinoline (CAS 1260657-40-6)
- 2-(2-Methyl-1,3-dioxolan-2-yl)propanal (CAS 79012-35-4)
- 1-(3-((2-Hydroxyethyl)(methyl)amino)piperidin-1-yl)ethanone (CAS 1353948-14-7)
- N-(4-acetamidophenyl)-2-bromoacetamide (CAS 883502-35-0)
- 2,2,4,6,6-Pentamethyl-3-Heptene (CAS 123-48-8)
- 8-((Benzyloxy)methyl)-1,4-dioxaspiro[4.5]decane (CAS 132452-42-7)
- 2-Chloro-N-(1-hydroxypropan-2-yl)acetamide (CAS 119907-19-6)
- Semaglutide Impurity 183 (CAS 159541-28-3)
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