4-Chloro-N-(4-hydroxynaphthalen-1-yl)-3-nitrobenzenesulfonamide CAS 420092-79-1
| CAS No. | 420092-79-1 |
| Molecular Formula | C16H11ClN2O5S |
| Molecular Weight | 378.79 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-Chloro-N-(4-hydroxynaphthalen-1-yl)-3-nitrobenzenesulfonamide (C16H11ClN2O5S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies 4-Chloro-N-(4-hydroxynaphthalen-1-yl)-3-nitrobenzenesulfonamide (CAS 420092-79-1), a certified reference material (molecular formula C16H11ClN2O5S, MW 378.79 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Chloro-N-(4-hydroxynaphthalen-1-yl)-3-nitrobenzenesulfonamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H11ClN2O5S |
| Molecular Weight | 378.79 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
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Recommended Standards
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- 7-Chloro-4-(trifluoromethyl)-1H-indole (CAS 1167055-96-0)
- N-(1-ethylpropyl)-Cyclopropanamine hydrochloride (1:1) (CAS 1193389-86-4)
- 1-Methyloxazolo[5,4-b]pyridin-2(1H)-one (CAS 144141-38-8)
- 4-(Piperidin-4-yl)isoindoline-1,3-dione hydrochloride (CAS 50534-34-4)
- 2-Cyano-N-[3-(piperidine-1-sulfonyl)-phenyl]-acetamide (CAS 554405-55-9)
- n-[1-(hydrazinecarbonyl)-2-phenyleth-1-en-1-yl]acetamide (CAS 15048-22-3)
- Anti-TF Antigen Peptide P30-1 trifluoroacetate salt (CAS 573664-50-3)
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