N-(5-Chloro-2-methylphenyl)-2-methylimidazo[1,2-a]pyridine-3-carboxamide CAS 478245-47-5

Purity 97%+In StockPharmaceutical Standards
CAS No.478245-47-5
Molecular FormulaC16H14ClN3O
Molecular Weight299.75 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N-(5-Chloro-2-methylphenyl)-2-methylimidazo[1,2-a]pyridine-3-carboxamide CAS 478245-47-5 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-(5-Chloro-2-methylphenyl)-2-methylimidazo[1,2-a]pyridine-3-carboxamide.

N-(5-Chloro-2-methylphenyl)-2-methylimidazo[1,2-a]pyridine-3-carboxamide (CAS 478245-47-5) is a high-purity analytical reference standard with the molecular formula C16H14ClN3O and a molecular weight of 299.75 g/mol.

Based on its molecular formula C16H14ClN3O, N-(5-Chloro-2-methylphenyl)-2-methylimidazo[1,2-a]pyridine-3-carboxamide contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 299.75 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), N-(5-Chloro-2-methylphenyl)-2-methylimidazo[1,2-a]pyridine-3-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC16H14ClN3O
Molecular Weight299.75 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentCl-containing
Nitrogen Atoms3

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