Vonoprazan Impurity 142 CAS CATO-C4X-1020142
| CAS No. | CATO-C4X-1020142 |
| Molecular Formula | C11H11FN2O |
| Molecular Weight | 206.22 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Vonoprazan Impurity 142 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Vonoprazan Impurity 142 (CAS CATO-C4X-1020142), a pharmacopoeial impurity reference standard (molecular formula C11H11FN2O, MW 206.22 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Vonoprazan Impurity 142 (C11H11FN2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C11H11FN2O |
| Molecular Weight | 206.22 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Vonoprazan Standards
- Vonoprazan Impurity 307 (CAS CATO-C4X-1020307)
- Vonoprazan Impuirty 128 (CAS 928324-50-9)
- Vonoprazan Fumarate Impurity 17 (CAS 1883595-38-7)
- Vonoprazan Impurity 196 (CAS CATO-C4X-1020196)
- Vonoprazan Impurity 244 (CAS CATO-C4X-1020244)
- Vonoprazan Impurity 210 (CAS CATO-C4X-1020210)
- Vonoprazan Impurity 65 (CAS 1610043-62-3)
- Vonoprazan Impurity 113 (CAS 1956309-28-6)
Recommended Standards
- (S)-1-[6-(4-Fluoro-1-pyrazolyl)-3-pyridyl]ethanamine (CAS 1980023-96-8)
- Acetylcysteine impurity 63 (CAS CATO-C4X-153263)
- 2-(3-pyridyl)-1,3-thiazole-4-carboxylic acid 2-(pyridin-3-yl)-1,3-thiazole-4-carboxylic acid 2-Pyridin-3-yl-thiazole-4-carboxylic acid 39067-29-3 (CAS 39067-29-3)
- Xanomeline Impurity 16 (CAS CATO-C4X-330116)
- Dirithromycin EP impurity A (CAS 26116-56-3)
- Lovastatin Impurity 26 (CAS CATO-C4X-168426)
- Pantoprazole Impurity 70 (CAS CATO-C4X-139970)
- Sodium (S)-2-hydroxy-4-(methylthio)butanoate (CAS 54641-20-2)
- 2-Bromo-1-methyl-1H-imidazole-4-carboxylic Acid (CAS 852181-03-4)
- Biapenem impurity 16 (CAS CATO-C4X-227316)
- (5-Amino-1-(3-chlorophenyl)-1H-pyrazol-4-yl)(furan-2-yl)methanone (CAS 618091-66-0)
- tert-Butyl 4-(2-(p-tolyl)acetyl)benzylcarbamate (CAS 1017781-77-9)
- Rel-((1R,2R)-2-phenylcyclopropyl)boronic acid (CAS 204378-97-2)
- Tau Peptide (277-291) trifluoroacetate salt (CAS 330456-40-1)
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