2-[(2,6-Dichlorophenyl)sulfanyl]-4-(4-fluorophenyl)pyridine-3-carbonitrile CAS 478245-91-9

Purity 97%+In StockPharmaceutical Standards
CAS No.478245-91-9
Molecular FormulaC18H9Cl2FN2S
Molecular Weight375.25 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-[(2,6-Dichlorophenyl)sulfanyl]-4-(4-fluorophenyl)pyridine-3-carbonitrile CAS 478245-91-9 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

2-[(2,6-Dichlorophenyl)sulfanyl]-4-(4-fluorophenyl)pyridine-3-carbonitrile (CAS 478245-91-9) is a high-purity analytical reference standard with the molecular formula C18H9Cl2FN2S and a molecular weight of 375.25 g/mol.

The molecular framework of 2-[(2,6-Dichlorophenyl)sulfanyl]-4-(4-fluorophenyl)pyridine-3-carbonitrile (C18H9Cl2FN2S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

CATO manufactures 2-[(2,6-Dichlorophenyl)sulfanyl]-4-(4-fluorophenyl)pyridine-3-carbonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC18H9Cl2FN2S
Molecular Weight375.25 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)14.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF/Cl-containing
Nitrogen Atoms2
Sulfur Atoms1

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