Methyl 1-(2,3-dichlorophenyl)-2,3,4,9-tetrahydro-1H-beta-carboline-3-carboxylate CAS 528524-81-4
| CAS No. | 528524-81-4 |
| Molecular Formula | C19H16Cl2N2O2 |
| Molecular Weight | 375.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Methyl 1-(2,3-dichlorophenyl)-2,3,4,9-tetrahydro-1H-beta-carboline-3-carboxylate is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Methyl 1-(2,3-dichlorophenyl)-2,3,4,9-tetrahydro-1H-beta-carboline-3-carboxylate (CAS 528524-81-4) is a high-purity analytical reference standard with the molecular formula C19H16Cl2N2O2 and a molecular weight of 375.25 g/mol.
Methyl 1-(2,3-dichlorophenyl)-2,3,4,9-tetrahydro-1H-beta-carboline-3-carboxylate (C19H16Cl2N2O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H16Cl2N2O2 |
| Molecular Weight | 375.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
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- 7-Bromo-1,6-naphthyridine-2-carboxylic acid (CAS 157848-47-5)
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