N'-[(1E)-(4-Chlorophenyl)methylidene]-3-[(4-fluorophenyl)methoxy]thiophene-2-carbohydrazide CAS 478246-50-3
| CAS No. | 478246-50-3 |
| Molecular Formula | C19H14ClFN2O2S |
| Molecular Weight | 388.84 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, N'-[(1E)-(4-Chlorophenyl)methylidene]-3-[(4-fluorophenyl)methoxy]thiophene-2-carbohydrazide (C19H14ClFN2O2S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 13.0, corresponding to approximately 13 ring(s) or double-bond equivalent(s). With a molecular weight of 388.84 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
N'-[(1E)-(4-Chlorophenyl)methylidene]-3-[(4-fluorophenyl)methoxy]thiophene-2-carbohydrazide (CAS 478246-50-3), molecular formula C19H14ClFN2O2S and molecular weight 388.84 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures N'-[(1E)-(4-Chlorophenyl)methylidene]-3-[(4-fluorophenyl)methoxy]thiophene-2-carbohydrazide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H14ClFN2O2S |
| Molecular Weight | 388.84 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Recommended Standards
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Why CATO?
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