(E)-3-((4-fluorobenzyl)oxy)-N'-(pyridin-4-ylmethylene)thiophene-2-carbohydrazide CAS 478246-51-4

Purity 97%+In StockPharmaceutical Standards
CAS No.478246-51-4
Molecular FormulaC18H14FN3O2S
Molecular Weight355.39 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(E)-3-((4-fluorobenzyl)oxy)-N'-(pyridin-4-ylmethylene)thiophene-2-carbohydrazide CAS 478246-51-4 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 355.39 g/mol gives (E)-3-((4-fluorobenzyl)oxy)-N'-(pyridin-4-ylmethylene)thiophene-2-carbohydrazide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

(E)-3-((4-fluorobenzyl)oxy)-N'-(pyridin-4-ylmethylene)thiophene-2-carbohydrazide (CAS 478246-51-4) is a high-purity analytical reference standard with the molecular formula C18H14FN3O2S and a molecular weight of 355.39 g/mol.

The molecular framework of (E)-3-((4-fluorobenzyl)oxy)-N'-(pyridin-4-ylmethylene)thiophene-2-carbohydrazide (C18H14FN3O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

As a certified reference material (CRM), (E)-3-((4-fluorobenzyl)oxy)-N'-(pyridin-4-ylmethylene)thiophene-2-carbohydrazide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC18H14FN3O2S
Molecular Weight355.39 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)13.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF-containing
Nitrogen Atoms3
Sulfur Atoms1

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